Omegreen Capsules (Omeprazole)

Adult dose

1. Adults 1) Gastric ulcer: Administer 20mg of omeprazole orally once daily per dose. If healing has not occurred after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other medicines, a dose of 40mg once daily usually results in healing within 8 weeks, although the healing time may vary from patient to patient. If the condition recurs, repeat treatment. 2) Short-term treatment of duodenal ulcer: Administer 20mg orally once daily per dose. If healing has not occurred after the initial 2 weeks of treatment, continue treatment for an additional 2 weeks. In patients who have not responded to other medicines, a dose of 40mg once daily usually results in healing within 4 weeks, although the healing time may vary from patient to patient. If the condition recurs, repeat treatment. 3) Reflux esophagitis: Administer 20mg orally once daily per dose. If healing has not occurred after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other medicines, a dose of 40mg once daily usually results in healing within 8 weeks, although the healing time may vary from patient to patient. If the condition recurs, repeat treatment. 4) Zollinger-Ellison syndrome: The initial dose is 60mg orally once daily per dose. Continue treatment with the dose appropriately adjusted for the individual. More than 90% of patients respond to doses of 20 - 120mg daily; if administering more than 80mg daily, divide the dose into 2 doses per day. 5) Maintenance therapy for severe reflux esophagitis and peptic ulcers that are difficult to treat: Administer 20mg orally once daily per dose. If the condition recurs, the dose may be increased to 40mg once daily per dose. 6) Antibiotic combination therapy to prevent recurrence of duodenal ulcers infected with Helicobacter pylori: - Dual therapy: Administer this medicine 20mg and amoxicillin 750 - 1000mg together 2 times daily for 2 weeks. - Triple therapy: Administer this medicine 40mg once daily or 20mg 2 times daily in combination with the following antibiotics. ① Administer clarithromycin 250mg and metronidazole 400mg 2 times daily for 1 week, or ② Administer amoxicillin 1g and clarithromycin 500mg 2 times daily for 1 week. If the treatment response is insufficient, omeprazole monotherapy may be continued. 7) Treatment of symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): Administer 20mg orally once daily per dose. Healing is generally possible after taking the medicine for 2-4 weeks. 8) Treatment of gastric or duodenal ulcers or erosions caused by nonsteroidal anti-inflammatory drugs (NSAIDs): Administer 20mg orally once daily per dose. If healing has not occurred after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. 9) Maintenance regimen for prevention of gastric or duodenal ulcers or erosions and dyspeptic symptoms caused by NSAID use in patients on long-term NSAID therapy with a history of gastroduodenal lesions: Administer 20mg orally once daily per dose. * When taking this medicine, swallow it whole with at least half a glass of water. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used in patients who are allergic to its components. Caution is needed when administering to patients with gastric ulcers that may be malignant as symptom relief could delay diagnosis. This medication should not be used with certain antiviral agents such as atazanavir or rifabutin-containing products. It should not be administered to patients with hereditary lactose intolerance. Patients with impaired liver function need to adjust the dosage, especially those with severe liver damage should not exceed 20mg per day. Elderly patients should be administered carefully, with vigilance for potential adverse reactions. Symptoms such as headache, drowsiness, dizziness may occur, and liver enzyme levels may rise, thus the medication should be discontinued if liver dysfunction is suspected. Gastrointestinal disorders such as diarrhea, abdominal pain, and nausea are common, and if allergic reactions such as skin rash or itching occur, the drug should be discontinued immediately. Rarely, hypersensitivity reactions including angioedema or anaphylactic shock may occur, so caution is advised. This drug may interact with several other medications; if taking another medicine, consultation with a doctor or pharmacist is essential. Particular care should be taken when used with medications like warfarin, diazepam, and phenytoin as blood concentration changes need to be monitored. Long-term use may increase the risk of fractures, so it's best to administer at the lowest effective dose and for the shortest duration possible. Patients who take this medication for more than three months may develop hypomagnesemia, and should have their magnesium levels checked regularly. Women who are pregnant or may become pregnant should use this medication cautiously, and nursing mothers should avoid it or discontinue breastfeeding. Safety in pediatrics has not been established, hence its use is not recommended. In cases of overdose, symptoms such as vomiting, diarrhea, and headaches may occur; serious side effects are rare, but immediate medical attention should be sought. This medication should be kept out of reach of children, not transferred to other containers, and the bottle cap should be tightly closed after use.

Headache, drowsiness, dizziness, insomnia, paresthesia, feeling faint, vertigo, confusion, agitation, aggression, hallucinations, depression, elevated liver enzymes, jaundice, hepatitis, liver failure, encephalopathy, interstitial nephritis, diarrhea, flatulence, constipation, nausea, vomiting, abdominal pain, abdominal distension, dry mouth, stomatitis, gastrointestinal candidiasis, erythema, rash, urticaria, itching, dermatitis, vesicular rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, photosensitivity, alopecia, angioedema, fever, bronchospasm, interstitial nephritis, anaphylactic shock, chest pain, tachycardia, bradycardia, palpitations, leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, back pain, arthralgia, muscular weakness, myalgia, gynecomastia, cough, asthenia, fatigue, peripheral edema, increased sweating, blurred vision, visual impairment, taste disorder, breast pain, breast lump, hyponatremia, erectile dysfunction, Clostridium difficile-associated diarrhea, hypomagnesemia, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms, systemic lupus erythematosus, discoid lupus erythematosus, gastric polyps, hypocalcemia, hypokalemia, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, acute interstitial nephritis, nausea, apathy, depression, confusion

This medication may be sensitive to air and moisture, hence it should be stored in a tightly sealed container. Also, avoid extremely hot or cold places, and store at room temperature between 1 to 30 degrees Celsius.

Appearance

A hard capsule with a reddish-brown upper part and a pinkish-red lower part filled with light yellow enteric-coated granules

Package unit

28 capsules/bottle