Naproxen SR Soft Capsules (Naproxen)

Adult dose

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis: Administer naproxen 250-500 mg orally twice a day (every 12 hours). 2. Acute gout: Administer 750 mg naproxen orally as a loading dose, then 250 mg orally every 8 hours until the attack subsides. 3. Musculoskeletal disorders, postoperative pain, pain after tooth extraction, dysmenorrhea, tendinitis, bursitis: Administer naproxen as such.

This medication may increase the risk of gastrointestinal bleeding in patients who regularly consume more than three alcoholic drinks per day; therefore, they should consult a doctor or pharmacist. This medication can affect the cardiovascular system and may cause serious heart issues such as thrombosis, myocardial infarction, and stroke, so extra caution is advised for those with heart disease or risk factors. This medication can cause serious problems such as gastrointestinal and intestinal bleeding, ulcers, and perforations; thus, caution is particularly important for the elderly or those with a history of gastrointestinal disorders. Patients with peptic ulcers, severe blood disorders, liver, heart, or kidney dysfunction, hypertension, or allergies to this medication or nonsteroidal anti-inflammatory drugs should not use this medication. Caution is necessary for those with a history of peptic ulcers, blood disorders, bleeding tendencies, liver or kidney dysfunction, heart problems, hypertension, allergies, asthma, autoimmune diseases, or the elderly. If unusual symptoms such as difficulty breathing, low blood pressure, rash, hematemesis, gastrointestinal bleeding, blood disorders, liver dysfunction, kidney issues, severe headaches, skin rashes, hearing impairments, swelling, or palpitations occur while taking this medication, it should be discontinued immediately and a doctor consulted. This medication should be taken at the lowest dosage for the shortest duration possible, and regular blood tests and liver/kidney function assessments are necessary for chronic conditions. Consult your doctor if you are taking other non-steroidal anti-inflammatory drugs, anti-epileptics, hypoglycemic agents, beta-blockers, ACE inhibitors, diuretics, or anticoagulants, as interactions may occur. This medication should not be used in late pregnancy due to the risk of ductus arteriosus closure in the fetus, and caution is advised after mid-pregnancy due to potential kidney dysfunction and oligohydramnios in the fetus. This medication can be excreted into breast milk and may affect newborns; thus, it is recommended not to take it while breastfeeding. Safety has not been established for use in infants, and it is advisable not to administer it to them. The elderly should start with a small amount due to a higher risk of gastrointestinal bleeding. Overdose may result in symptoms such as drowsiness, chest discomfort, dyspepsia, nausea, and vomiting; immediate medical attention should be sought for proper treatment. This medication should be kept out of reach of children and should not be transferred to another container for safety.

Serious side effects

• Urticaria
• swelling
• chest tightness
• difficulty breathing
• cold sweat
• hypotension (shock symptoms)
• fever
• wheezing
• coughing
• hematemesis

Mild side effects

• Nausea
• stomach pain
• abdominal pain
• vomiting
• loss of appetite
• dyspepsia
• heartburn
• diarrhea
• constipation
• stomatitis

Drug interactions

Do not take this medication in conjunction with other non-steroidal anti-inflammatory drugs (NSAIDs) and naproxen derivatives. In combination with hydantoins, sulfonamides, sulfonylurea hypoglycemic agents, propranolol and other beta-blockers, ACE inhibitors, loop diuretics and thiazide diuretics, probenecid, aspirin, lithium, methotrexate, coumarin anticoagulants, zidovudine, and quinolone antibiotics.

This medication should be stored in a tightly closed container to prevent air or moisture entry, preferably at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the efficacy of the medication longer.

Appearance

Dark blue oblong soft capsule containing a clear colorless or blue liquid

Package unit

10 capsules/PTP