Medication info

Maorex Tablets 0.5 mg (Rasagiline Mesylate)

Prescription medicationTabletOralExpired
Ingredient · strength
Rasagiline Mesylate›0.78mg / 1 tablet
Manufacturer / importer
Chodang Pharmaceutical Co., Ltd.
Appearance
White round tablet
Packaging
30 tablets/PTP [10 tablets/PTP*3]
Approval status
Expired

MFDS item code 202003583 · Approved 2020.05.18

This product's status changed to Expired on 2025.05.18. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of idiopathic Parkinson’s disease
Who takes it
Adults
Adult dose
This drug is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended starting dose in patients taking levodopa is 0.5mg once daily. If well tolerated but the clinical response is inadequate, the dose may be increased to 1mg once daily. This drug may be taken with or without food.

Ingredients

Manufacturer
Chodang Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson’s disease

  • Idiopathic Parkinson's disease
  • motor fluctuation symptoms
View approved original text

This medication is used for the treatment of idiopathic Parkinson's disease. Initially, it is administered alone or as an adjunct therapy with dopamine agonists. Additionally, it is also used as an adjunct in patients experiencing motor fluctuations during levodopa treatment to help alleviate symptoms. This drug is effective in the improvement and treatment of Parkinson's disease symptoms.

How to take

Adult dose

This drug is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended starting dose in patients taking levodopa is 0.5mg once daily. If well tolerated but the clinical response is inadequate, the dose may be increased to 1mg once daily. This drug may be taken with or without food.

Precautions

This medication should not be administered to certain patients. First, patients allergic to the main ingredient or other components of this medication should not take it. Moreover, patients currently taking or who have recently discontinued other MAO inhibitors within the last two weeks should not use this medication. Patients taking specific medications such as pethidine, tramadol, or dextromethorphan should also not use this drug. This medication is not to be administered to patients with moderate to severe liver impairment. Various adverse reactions may occur during the use of this drug. Commonly reported side effects include headache, dizziness, depression, hallucinations, dermatitis, musculoskeletal pain, nausea, vomiting, constipation, and insomnia. Additionally, some patients may experience symptoms such as dyskinesia, orthostatic hypotension, accidental injury, or falling. If such symptoms occur, immediate consultation with a healthcare professional is necessary. This medication should be used with caution in patients with impaired liver function and should not be given to patients with moderate to severe liver dysfunction. No dosage adjustment is needed for patients with mild renal impairment, but sufficient information is lacking for patients with severe renal impairment. This drug may affect the ability to drive or operate machinery, so if drowsiness or sudden sleepiness occurs during treatment, patients should avoid hazardous activities. Caution is also needed as interactions may occur when taken with sedatives, central nervous system depressants, or certain antibiotics. Serious side effects may occur when this medication is used in conjunction with other MAO inhibitors, certain analgesics, or antidepressants, so it is essential to discuss this with a doctor. Particularly, it is safer to start this medication after discontinuing an antidepressant for a certain period. Women who are pregnant or breastfeeding should use this medication with caution, as there is insufficient information regarding its transmission to breast milk, and consultation with a professional is needed. Safety and efficacy in pediatric patients have not been established, so it is advisable not to use this drug in patients under 18 years of age. In the case of overdose, serious symptoms such as mania, hypertensive crisis, or serotonin syndrome may occur, so it is essential to avoid overdose and to immediately inform healthcare personnel for appropriate treatment if an overdose has occurred. This medication should be kept out of the reach of children and stored at temperatures between 1 and 25 degrees Celsius. Care should be taken not to transfer it to another container, as this may negatively affect quality.

Side effects

  • influenza
  • skin cancer
  • leukopenia
  • allergy
  • loss of appetite
  • depression
  • hallucinations
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • abdominal distension
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • cervical pain
  • arthritis
  • urge incontinence
  • fever
  • fatigue
  • peripheral edema
  • falls
  • arthralgia
  • cough
  • insomnia
  • nausea
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • dyspepsia
  • hernia
  • infection
  • gingivitis
  • traumatic injury
  • weight loss
  • tendinitis
  • dyskinesia
  • drowsiness
  • sensory disturbances
  • ataxia
  • muscle spasms
  • myasthenia
  • loss of appetite
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • orthostatic hypotension
  • petechiae
  • bleeding
  • melanoma
  • confusion
  • carpal tunnel syndrome
  • balance disorders
  • hypotension
  • excessive drowsiness
  • acute renal failure
  • malignant hyperthermia
  • general weakness
  • pulmonary tuberculosis
  • semi-consciousness
  • gait disturbances
  • ocular motor seizures
  • facial paralysis
  • spinal stenosis
  • exacerbation of Parkinson's disease
  • subdural hemorrhage
  • pneumonia
  • vertebral fracture
  • rib fracture
  • tendon injury
  • pelvic fracture
  • leg fracture
  • upper limb fracture
  • low back pain
  • knee arthroplasty
  • herniated disc
  • hypoglycemia
  • weight loss
  • dysuria
  • vaginitis
  • conjunctival injection
  • diplopia
  • visual impairment
  • skin hypertrophy
  • palpitations
  • arrhythmia
  • gastrointestinal discomfort
  • gastroesophageal reflux
  • increased salivation
  • irritable bowel syndrome
  • fissured tongue
  • increased bowel frequency
  • unspecified intestinal disease
  • esophagitis
  • excessive gastric acid
  • gastroesophageal reflux disease
  • gastric irritation
  • gastritis
  • gastrointestinal motility disorder
  • periodontitis
  • Helicobacter pylori gastritis
  • anemia
  • leg pain
  • chest pain
  • syncope
  • periorbital edema
  • facial flushing
  • pain
  • hallucination
  • sleep disorders
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosexual disorders
  • paresthesia
  • tremor
  • freezing phenomenon
  • limb tremors
  • axial muscle cramping syndrome
  • leg cramps
  • polyuria
  • shaking
  • stuttering
  • voice disorders
  • vocal cord paralysis
  • speech disorders
  • pruritus
  • urticaria
  • boils
  • hair loss
  • contusion
  • sputum abnormalities
  • increased sputum
  • common cold
  • bronchitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container, protected from air and moisture. The appropriate storage temperature is a cool place between 1 and 25 degrees Celsius.

Appearance and packaging

Appearance

White round tablet

Package unit

30 tablets/PTP [10 tablets/PTP*3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.