Itraconazole Tablet (Itraconazole Solid Dispersion)

Adult dosage

It is preferable to take this medicine immediately after a meal. Vulvovaginal candidiasis: Take itraconazole 200 mg twice daily (morning and evening) for 1 day, or 200 mg once daily for 3 days. Tinea versicolor: Take 200 mg once daily for 7 days. Tinea corporis and tinea cruris: Take 100 mg once daily for 15 days. Tinea manuum (interdigital) and tinea pedis (interdigital): Take 100 mg once daily for 15 days. Tinea manuum (palmar) and tinea pedis (plantar): Take 100 mg once daily for 30 days or 200 mg twice daily for 7 days. Oral candidiasis: Take 100 mg once daily for 15 days. Fungal keratitis: Take 200 mg once daily for 21 days. Onychomycosis, pulse therapy: Take 200 mg twice daily for 1 week, followed by a 3-week treatment-free period; this constitutes 1 cycle. Administer up to 2 cycles for fingernail infection only, and up to 3 cycles for toenail infection. Onychomycosis, continuous therapy: Take 200 mg once daily for 3 months. In patients with reduced immune function, such as those with neutropenia or AIDS or those who have undergone organ transplantation, the oral bioavailability of this medicine may be reduced; if necessary, increase the dose twofold. Aspergillosis: 200mg once daily for 2～5 months. For invasive or disseminated disease, increase to 200mg twice daily. Candidiasis: 100～200mg once daily for 3 weeks～7 months. Cryptococcal meningitis: 200mg twice daily for 2 months～1 year. Maintenance therapy: 200mg once daily. Paracoccidioidomycosis: 100mg once daily for 6 months.

This medication should be used with caution in patients with poor heart function, especially those with a history of congestive heart failure or impaired ventricular function as it may pose life-threatening risks. Patients with allergic reactions to this medication or hypersensitivity to its components should not use it. Severe side effects may occur when taken with certain specific medications, so it should not be combined with cardiac medications, certain analgesics, antiarrhythmics, anticancer drugs, or antipsychotics. Women who are pregnant, possibly pregnant, or breastfeeding should not take this medication, and if there is a chance of pregnancy, effective contraceptive measures should be taken after discontinuation of the drug until the next menstrual period. Patients with liver dysfunction should have regular liver function tests when using this medication, and it is advisable to avoid its use if there is a high risk of liver damage. Patients with decreased kidney function may also require careful dose adjustment. This medication may rarely cause side effects such as headache, nausea, abdominal pain, liver function abnormalities, skin rash, etc., and immediate consultation with medical personnel is necessary if there are any abnormal symptoms. Dizziness, vision or hearing disturbances may occur during treatment, so caution is needed when driving or operating machinery. This medication may not be well-absorbed in low acidity states, so patients taking acid-reducing medications may benefit from taking it with acidic beverages. There is no specific antidote in cases of overdose, so it is important to adhere to recommended dosages and avoid excess. Care should be taken when administering this medication to children or the elderly, especially the elderly, to consider potential liver, kidney, and heart function impairments for dose adjustments. This medication should be stored out of reach of children, and kept in its original container to prevent degradation or misuse.

Decreased myocardial contractility, ventricular arrhythmia, QT prolongation, headache, nausea, abdominal pain, rhinitis, sinusitis, upper respiratory infection, leukopenia, hypersensitivity, taste disorder, sensory disturbance, paresthesia, tinnitus, constipation, diarrhea, dyspepsia, abdominal distension, vomiting, abnormal liver function, hyperbilirubinemia, itching, rash, urticaria, pollakiuria, erectile dysfunction, menstrual disorders, edema, granulocytopenia, thrombocytopenia, anaphylactoid reaction, hyperglycemia, hyperkalemia, hypokalemia, hypomagnesemia, confusion, peripheral neuropathy, dizziness, drowsiness, tremors, heart failure, left ventricular failure, tachycardia, hypertension, hypotension, pulmonary edema, speech disorders, cough, gastrointestinal disorders, liver failure, hepatitis, jaundice, erythematous rash, sweating, myalgia, arthralgia, renal impairment, urinary incontinence, generalized edema, facial edema, chest pain, fever, pain, fatigue, chills, increased alanine aminotransferase, increased aspartate aminotransferase, increased serum alkaline phosphatase, increased serum lactate dehydrogenase, increased blood urea, increased gamma-glutamyl transferase, elevated liver enzymes, abnormal urinalysis, leukocytosis, eosinophilia, anemia, vascular edema, serum sickness, vasogenic edema, anaphylaxis, anaphylactic shock, allergic reaction, diplopia, visual impairment, hearing loss, ventricular extrasystole, atrial block, palpitations, increased intestinal motility, belching, glossitis, stomatitis, abdominal and lumbar pain, pancreatitis, elevated serum total protein, increased total bilirubin, elevated LAP, loss of appetite, malaise, dark urine, mucosal membrane syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, Riel syndrome, erythema multiforme, hair loss, phototoxic reaction, exfoliative dermatitis, leukocytoclastic vasculitis, acute generalized exanthematous pustulosis, increased BUN, positive urine protein reaction, positive urine sugar reaction, decreased libido, drowsiness, shoulder stiffness, insomnia, chest pain, increased serum triglyceride levels, flushing, increased serum uric acid levels, elevated serum potassium levels, transient asymptomatic decrease in left ventricular ejection fraction, heart failure, decreased cardiac output, deep vein thrombosis, difficulty breathing, acute liver failure, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, increased serum creatine phosphokinase

This medication should be stored in a tightly sealed container that does not allow air to pass through, and it is recommended to be kept at a temperature between 1 and 30 degrees Celsius. This will help maintain the drug's effectiveness.

Appearance

White or pale yellow round film-coated tablet

Package unit

28 tablets/bottle, 100 tablets/bottle