Enconacapsule 100mg (Itraconazole)

Adult dosage

It is preferable to take this medication immediately after a meal. Swallow the capsules whole. Vulvovaginal candidiasis: Administer itraconazole 200 mg twice daily (morning and evening) for 1 day, or 200 mg once daily for 3 days. Tinea versicolor: Administer 200 mg once daily for 7 days. Tinea corporis and tinea cruris: Administer 100 mg once daily for 15 days. Tinea manuum (interdigital) and tinea pedis (interdigital): Administer 100 mg once daily for 15 days. Tinea manuum (palmar) and tinea pedis (plantar): Administer 100 mg once daily for 30 days, or 200 mg twice daily for 7 days. Oropharyngeal candidiasis: Administer 100 mg once daily for 15 days. Fungal keratitis: Administer 200 mg once daily for 21 days. Administer 200 mg twice daily for 1 week, followed by a 3-week drug-free interval; this constitutes 1 cycle. Administer up to 2 cycles for infection limited to the fingernails and up to 3 cycles for infection of the toenails. Continuous therapy: Administer 200 mg once daily for 3 months. In patients with impaired immune function, such as those with neutropenia or AIDS or those who have undergone organ transplantation, the oral bioavailability of this medication may be reduced; if necessary, increase the dose to twice the usual dose. Aspergillosis: 200mg once daily for 2~5 months. For invasive or disseminated disease, increase to 200mg twice daily. Candidiasis: 100~200mg once daily for 3 weeks~7 months. Cryptococcal meningitis: 200mg twice daily for 2 months~1 year. Maintenance therapy (for patients with AIDS only): 200mg once daily. Paracoccidioidomycosis: 100mg once daily for 6 months.

This drug may pose a life-threatening risk to patients with weakened heart function, especially those with congestive heart failure or a history of it, and should not be administered except in special cases. If symptoms of heart failure occur while taking this drug, administration should be discontinued immediately. This medication can reduce the contractility of the heart muscle, requiring caution in individuals with heart conditions. Individuals allergic to this medication or its components should not take it. Additionally, co-administration with specific medications may dangerously increase drug concentrations in the blood, so it should not be taken with contraindicated medications. Women who are pregnant or capable of becoming pregnant, as well as nursing mothers, should avoid using this drug. Patients with poor liver function should undergo regular liver function tests due to its metabolism by the liver, and if there is a high risk of liver damage, administration should be avoided. Patients with impaired kidney function may require dosage adjustments due to potentially decreased bioavailability. Patients with weakened immune systems or specific systemic fungal infections should monitor the drug's effects and adjust dosage as needed. This drug may cause side effects such as headache, nausea, abdominal pain, diarrhea, and rarely more severe side effects such as liver function abnormalities, skin rash, and neurological issues, so if any unusual symptoms occur, consultation with a physician is necessary. This drug can interact with many other medications; therefore, other concurrent medications should be disclosed, especially when taking heart disease treatments, anticoagulants, antipsychotics, anticancer drugs, and antivirals. It is recommended to take this medication with acidic beverages as absorption may decrease in low-acid environments. Caution should be exercised when driving or operating machinery due to the potential for dizziness, visual disturbances, or hearing loss as side effects. In case of overdose, symptomatic treatment should be provided as there is no specific antidote for this drug, and it is not removed by hemodialysis. Keep this medication out of reach of children and store it in its original container to prevent degradation or misuse.

headache, nausea, abdominal pain, rhinitis, sinusitis, upper respiratory tract infection, leukopenia, hypersensitivity, taste disorder, sensory impairment, sensory abnormalities, tinnitus, constipation, diarrhea, dyspepsia, bloating, vomiting, liver dysfunction, hyperbilirubinemia, pruritus, rash, urticaria, polyuria, erectile dysfunction, menstrual disorders, edema, granulocytopenia, thrombocytopenia, anaphylactoid reaction, hyperglycemia, hyperkalemia, hypokalemia, hypomagnesemia, altered mental state, peripheral neuropathy, dizziness, drowsiness, tremor, heart failure, left ventricular failure, tachycardia, hypertension, hypotension, pulmonary edema, voice disorder, cough, gastrointestinal disorders, hepatic failure, hepatitis, jaundice, erythematous rash, hyperhidrosis, myalgia, arthralgia, renal impairment, incontinence, generalized edema, facial edema, chest pain, fever, pain, fatigue, chills, increased alanine aminotransferase, increased aspartate aminotransferase, increased serum alkaline phosphatase, increased serum lactate dehydrogenase, increased blood urea, increased gamma-glutamyl transferase, increased liver enzymes, abnormal urinalysis, leukocytosis, eosinophilia, anemia, vascular edema, serum sickness, angioedema, anaphylaxis, anaphylactic shock, allergic reaction, diplopia, visual impairment, hearing loss, ventricular premature contraction, atrial block, palpitations, increased bowel movement, belching, glossitis, stomatitis, abdominal pain in the lower back area, pancreatitis, elevated serum total protein, increased total bilirubin, elevated LAP, appetite loss, lethargy, brown urine, increased liver enzyme levels, Stevens-Johnson syndrome, toxic epidermal necrolysis, Riel syndrome, erythema multiforme, hair loss, photosensitivity reaction, exfoliative dermatitis, leukocytoclastic vasculitis, acute generalized exanthematous pustulosis, elevated BUN, positive urine protein test, positive urine glucose test, decreased libido, drowsiness, shoulder stiffness, insomnia, chest pain, elevated serum triglycerides, flushing, elevated serum uric acid, elevated serum potassium, serum sickness, angioedema, anaphylaxis reaction, hypertriglyceridemia, tremor, visual impairment, transient hearing loss, permanent hearing loss, congestive heart failure, dyspnea, pancreatitis, significant hepatotoxicity, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, erythema multiforme, exfoliative dermatitis, leukocytoclastic vasculitis, hair loss, photosensitivity, increased serum creatine phosphokinase activity

This medication should be stored in a tightly sealed container that is well-ventilated, preferably at room temperature between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness over time.

Appearance

A hard capsule with a blue upper part and a pink lower part filled with white or grayish round pellets

Package unit

Bottle - 30 capsules/bottle, Bottle - 100 capsules/bottle