Acvi Tablets (Acyclovir)

Adult administration

1. Treatment of herpes simplex virus infections - Acyclovir 200 mg orally 5 times a day at 4-hour intervals for 5 days. - Treatment may be extended for severe initial infections. - In cases of severe immunocompromised patients or gastrointestinal absorption disorders, the dose may be increased to 400 mg or administered intravenously. 2. Prevention of herpes simplex infections (patients with normal immune function) - Administer 200 mg orally 4 times a day at approximately 6-hour intervals.

Child administration

1. Treatment of herpes simplex infections and prevention in patients with impaired immune function - Age 2 and older: follow adult dosing. - Under 2 years: administer half of the adult dose. - No definitive data for the prevention of herpes simplex virus infections in patients with normal immune function.

This medication should not be used in patients with known allergies to this drug or its components. Patients with impaired kidney function are at risk of experiencing neurological reactions while using this drug, so caution is necessary. Patients with impaired liver function should also use this drug cautiously as liver function may worsen with its use. Extra caution is advised when administering this drug to infants and young children, using the minimum effective dose when necessary. Elderly patients often have decreased kidney function, which may increase the concentration of this drug, so dosage and administration intervals should be adjusted accordingly. Rarely, this drug may cause serious allergic reactions such as anaphylactic shock; if symptoms such as low blood pressure, breathing difficulties, or chest tightness occur, administration should be stopped immediately and appropriate treatment should be sought. Skin reactions such as photosensitivity, rashes, fever, vesicles, or hives may develop, and if these occur, the medication should be discontinued, and a doctor consulted. Rarely, severe skin disorders such as Stevens-Johnson syndrome or toxic epidermal necrolysis may occur, so skin condition should be carefully monitored. Neurological symptoms may include altered consciousness, confusion, hallucinations, seizures, drowsiness, and anxiety, particularly in elderly patients or those with kidney impairment. Signs of impaired kidney function may include renal failure, hematuria, or proteinuria; kidney function should be regularly monitored. Blood abnormalities such as leukopenia, anemia, or bleeding may occur, so blood tests to assess the situation are important. Signs of liver dysfunction may include hepatitis, jaundice, or increased liver function test results; liver health should be closely monitored. Gastrointestinal symptoms may include gastritis, nausea, vomiting, diarrhea, or abdominal pain; if these symptoms are severe, the medication should be discontinued and a doctor consulted. Adequate hydration is necessary during treatment with this drug; particularly with high doses, it is important to drink plenty of water to prevent dehydration and to reduce the risk of kidney toxicity. This medication should be administered as soon as possible after the onset of symptoms, ideally within 5 days of herpes zoster or chickenpox symptom onset. For the treatment of recurrent genital herpes, consult a doctor on whether to continue use for more than a year. Consciousness-related disturbances may occur during treatment; caution is advised against operating vehicles or hazardous machinery. This medication may interact with other drugs, so it is important to inform your doctor, especially if using drugs that affect kidney function or certain other medications. Pregnant women or women who may become pregnant should carefully consider the risks and benefits of using this medication, and it is advisable to discontinue breastfeeding while taking it. In the event of an overdose, symptoms of kidney damage or central nervous system abnormalities may occur, so immediate medical assistance should be sought, and blood dialysis may be required if necessary.

Serious side effects

Anaphylactic shock, anaphylaxis-like reactions, hypotension, dyspnea, chest tightness, hives, mucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), jaundice, altered consciousness, seizures, epileptic seizures, renal failure, severe edema, edema accompanied by hypertension, sudden severe headache.

Mild side effects

• Photosensitivity reactions
• fixed drug eruption
• rashes
• fever
• vesicles
• urticarial erythema
• alopecia
• erythema multiforme
• altered consciousness
• disorientation

This medication may be sensitive to air and humidity, so it must be stored in a tightly sealed container. It is best stored at room temperature between 1 to 30 degrees Celsius. This will help maintain the efficacy of the drug for a longer period.

Appearance

Light blue round tablets

Package unit

Bottle - 30 tablets/bottle, Bottle - 200 tablets/bottle