Medication info

Betriol Gel

Prescription medicationExpired
Ingredient · strength
Calcipotriol Monohydrate›52.2μg / 1gBetamethasone Dipropionate›0.643mg / 1g
Manufacturer / importer
주식회사더유제약
Appearance
Colorless or whitish almost transparent gel
Packaging
30 grams/bottle
Approval status
Expired

MFDS item code 202003309 · Approved 2020.05.07

This product's status changed to Expired on 2025.05.07. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Topical treatment for moderate to severe scalp psoriasis and plaque psoriasis
Who uses it
Adults · Children
Adult dosage
This medication should be applied once daily to the affected area. Use on the scalp is recommended for 4 weeks, and on areas outside the scalp for 8 weeks. The daily amount should not exceed 15 g, and the maximum weekly dose should not exceed 100 g for adults. The surface area to which calcipotriol is applied should not exceed 30%. When used on the scalp, apply an amount between 1 g and 4 g to the entire affected area daily.
Children's dosage
The maximum weekly dose should not exceed 60 g for adolescents.

Ingredients

Manufacturer
주식회사더유제약

Efficacy & effects

Topical treatment for moderate to severe scalp psoriasis and plaque psoriasis

  • Moderate to severe scalp psoriasis
  • plaque psoriasis outside the scalp
View approved original text

This medication is used for moderate to severe scalp psoriasis and plaque psoriasis outside the scalp in adolescents aged 12 and older and adults. It effectively improves the symptoms of psoriasis on the scalp and skin, improving skin condition.

Dosage and Administration

Adult dosage

This medication should be applied once daily to the affected area. Use on the scalp is recommended for 4 weeks, and on areas outside the scalp for 8 weeks. The daily amount should not exceed 15 g, and the maximum weekly dose should not exceed 100 g for adults. The surface area to which calcipotriol is applied should not exceed 30%. When used on the scalp, apply an amount between 1 g and 4 g to the entire affected area daily.

Children's dosage

The maximum weekly dose should not exceed 60 g for adolescents.

Precautions

This medication should not be used in certain patients. Patients who have allergies or hypersensitivity to this drug or its ingredients should not use it. Patients with abnormalities in calcium metabolism should also avoid this medication. It is not suitable for certain types of psoriasis patients, such as those with guttate psoriasis or pustular psoriasis. Patients with severely impaired kidney or liver function should not use it. It is also not administered to children or patients with ear infections with perforated eardrums affecting facial or periocular skin. This medication should not be used in patients with skin diseases affected by bacterial, fungal, viral, or parasitic infections, as it may worsen symptoms. Patients with wounds, mucous membranes, ulcers, severe burns, specific dermatitis, acne, or genital itching should not use this medication. Pregnant women, women of childbearing age, breastfeeding women, elderly patients, and those with liver dysfunction or diabetes should use this drug with caution. This is because corticosteroid components in the drug can affect blood sugar levels. Using this medication may cause skin adverse reactions such as itching, dermatitis, rash, skin irritation, or aggravation of psoriasis. Rarely, hypersensitivity reactions or eye irritation have also been reported. Long-term use or use over large areas can lead to systemic side effects, such as adrenal suppression, increased blood sugar, or elevated intraocular pressure, so caution is advised. When using, always follow the prescribed dosage and method, and take care to avoid contact with sensitive areas such as the face, around the eyes, mouth, and genital skin, and mucous membranes. Always wash hands after use, and if symptoms worsen or do not improve, stop using the medication and consult a physician. Using this medication in large amounts or with occlusive dressings may lead to increased systemic absorption and serious side effects, so it is advisable to avoid them. Pregnant or breastfeeding women should only use this medication when necessary and under the doctor's judgment, as it may affect the fetus or infant. It is preferable not to use this medication in children, as its safety and efficacy have not been sufficiently established. Care should be taken as excessive use of this drug may elevate serum calcium levels, leading to dehydration, muscle weakness, or coma. Take care to prevent this medication from entering the eyes; if it does, rinse immediately with clean water, and seek ophthalmological attention if symptoms are severe. When storing the medication, keep it out of the reach of children, use it within 6 months of opening, and do not refrigerate. During the use of this medication, avoid excessive exposure to natural or artificial light and it is advised not to use it in conjunction with other corticosteroids.

Side effects and when to seek care immediately

Serious side effects

Hypersensitivity (hives, angioedema, facial swelling, etc.), hypercalcemia (polyuria, constipation, muscle weakness, confusion, coma), severe adrenal cortical dysfunction, cataracts, exacerbation of infections, metabolic control disturbances in diabetes, increased intraocular pressure and glaucoma, severe skin adverse reactions (serious rashes with high fever, blistering, skin peeling, oral/ocular mucosal pain), respiratory problems (shortness of breath or difficulty breathing, asthma attacks, cough and fever)

Mild side effects

  • Itching
  • skin infection
  • folliculitis
  • eye irritation
  • aggravation of psoriasis
  • dermatitis
  • erythema
  • rash
  • acne
  • skin burning sensation
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  • skin irritation
  • dry skin
  • skin lesions
  • peeling
  • pain at the application site
  • rebound reaction
  • bumps
  • pain
  • fever
  • redness
  • allergic contact dermatitis
  • heat rash
  • worsening of wounds
  • pressure sores
  • pustular psoriasis
  • steroid-induced acne
  • skin atrophy
  • capillary dilation
  • purpura
  • steroid-induced rosacea
  • peri-oral dermatitis
  • tinea corporis

Not everyone experiences these, and they can vary from person to person.

Storage

This drug is sensitive to light, so it must be stored in a light-blocking container. Additionally, it is best stored at a temperature between 9 and 30 degrees Celsius, which should not be too hot or too cold.

Appearance and packaging

Appearance

Colorless or whitish almost transparent gel

Package unit

30 grams/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.