Nellastone 20 mg (Rosuvastatin Calcium)

Adult dosage

Patients with primary hypercholesterolemia, combined hyperlipidemia, dysbetalipoproteinemia, and homozygous familial hypercholesterolemia may take this medication at any time of day regardless of meals. The initial dose is 5 mg once daily, and if greater reduction in LDL cholesterol levels is needed, the maintenance dose can be adjusted. The maintenance dose is typically 10 mg once daily, which is the dose most patients are adjusted to.

Children's dosage

The usual dosage range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 5 mg to 20 mg once daily. Clinical data for doses exceeding 20 mg in the pediatric population is not available.

This medication should not be used in certain patients. For instance, patients who are allergic to this medication, have severe liver dysfunction, have muscle disorders, have significantly impaired kidney function, or are pregnant or breastfeeding should not take this medication. Additionally, this medication may affect muscles, so caution is required in patients at risk for muscle pain or severe muscle damage. In such cases, it is important to regularly check muscle status through blood tests. Patients with liver function issues or those who consume high amounts of alcohol also need to undergo frequent liver function tests while taking this medication. Patients with conditions such as hypothyroidism or nephrotic syndrome should first treat these conditions before taking this medication. This medication can interact with other drugs; therefore, consultation with a healthcare professional is necessary, especially when taking certain antivirals, immunosuppressants, antibiotics, and fibrate medications. Concomitant use with certain drugs may increase the blood concentration of this medication and raise the risk of side effects. Women with the possibility of pregnancy must use effective contraception and should not take this medication during pregnancy. Additionally, breastfeeding women should avoid this medication. During the course of taking this medication, if symptoms such as muscle pain, muscle weakness, dizziness, or liver function abnormalities occur, they should immediately inform healthcare personnel. If there are severe skin reactions or allergic symptoms, the medication should be discontinued immediately, and medical advice should be sought. In cases of overdose, there are no specific antidotes, and treatment should be symptom-driven with monitoring of liver function and muscle enzymes. Caution is advised when driving or operating machinery, as dizziness may occur. Lastly, this medication may exhibit higher blood concentrations in Asians, so dosage adjustments may be necessary.

Serious side effects

Hypersensitivity reactions including angioedema, severe allergic reactions, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain of oral/ocular mucosa, severe adverse skin reactions, difficulty breathing or shortness of breath, asthma attack, respiratory abnormalities accompanied by cough and fever, respiratory problems, jaundice characterized by yellowing of skin or eyes, profound lethargy, liver abnormalities

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash and hives
• myalgia
• weakness
• thrombocytopenia

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication and ensure safe usage.

Appearance

Pink, round film-coated tablets

Package unit

100 tablets/bottle, 30 tablets/bottle