Clarithromycin Tablets 250 mg

Adult dosage

○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcer: Administer 500mg (potency) of this medicine three times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children 12 years of age and older: same as adults For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used in patients with allergies to specific ingredients or who have experienced hypersensitivity. It should also be avoided in patients with certain heart diseases or severely impaired liver or kidney function. It is safest not to use during pregnancy or breastfeeding. Caution is required as serious side effects may appear when taken with other specific medications. During treatment, it is essential to monitor for allergic reactions, gastrointestinal issues, skin rashes, neurological symptoms, etc. If symptoms such as irregular heartbeat or liver dysfunction appear, the medication should be stopped immediately, and a doctor should be consulted. Elderly patients or those with impaired liver or kidney function may require dose adjustments, so it's important to consult with a healthcare professional. This medication has a high potential for drug interactions, so all medications currently taken should be reported to the healthcare provider and carefully managed. In case of overdose, gastrointestinal disturbances or neurological symptoms may occur, necessitating immediate treatment. Dizziness or confusion may occur while driving or operating machinery, so caution is advised. Prolonged use or repeated administration of this medication may result in resistant bacteria, so it should only be taken for the exact duration prescribed by a doctor. Women who may become pregnant should check for pregnancy before taking this medication, and those who are breastfeeding should avoid it. The safety for children or infants under a specific age has not been sufficiently established, hence caution is warranted in usage. If symptoms like diarrhea or abdominal pain worsen during treatment, the healthcare provider should be notified immediately.

Shock, anaphylactic symptoms, dyspnea, seizures, erythema, rash, pruritus, urticaria, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, spasms, dry mouth, transient teeth discoloration, pancreatitis, increased amylase, taste disturbance, decreased appetite, constipation, stool discoloration, hematochezia, eosinophilic pulmonary infiltrate, interstitial pneumonia, fever, cough, chest X-ray abnormalities, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, derealization, seizures, tremor, numbness, behavior changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, elevated liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste disorder, hearing loss, paresthesia, arthralgia, myalgia, olfactory disorder, tinnitus, auditory impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, petechial rash, acute generalized exanthematous pustulosis, muscle cramps, musculoskeletal rigidity, myalgia, myopathy, elevated serum creatinine, elevated serum urea, renal failure, nephritis, vein inflammation at the injection site, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin/globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, urine color abnormality

This medication is sensitive to light and must be stored in a special container that blocks light. Additionally, it is important to store the medication at room temperature between 15 degrees and 30 degrees to maintain its efficacy.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle