Alitnnon Soft Capsule 30 mg (Alitretinoin)

Adult dose

Take 10~30mg once daily with or immediately after a meal. It is preferable to take it at the same time each day. The initial dose is alitretinoin 30mg, reduced to 10mg according to adverse reactions. Patients with diabetes, obesity, cardiovascular risk factors, or dyslipidemia: Administer an initial dose of 10mg and, if necessary, increase to 30mg according to tolerability and effect. Periodic monitoring of blood lipid profiles and blood glucose may be necessary during treatment with this medicine. Discontinue treatment as soon as the hands are clear or almost clear, or the treatment goal has been achieved. If hand eczema remains severe after the initial 12 weeks of treatment, discontinue treatment. Also discontinue treatment if the treatment goal has not been achieved by week 24.

This medication poses a very high risk of causing severe congenital malformations if used during pregnancy; therefore, women who are pregnant or may become pregnant must not take it. Pregnancy tests should be conducted prior to initiation of treatment and periodically during treatment; effective contraception must be used, and it should continue for a period after discontinuing treatment. Severe side effects such as acute pancreatitis could occur if triglyceride levels are very high; therefore, regular blood tests should be performed to monitor lipid levels. It is safest when prescribed by a specialist experienced in systemic retinoid therapy, and it should be avoided in patients with liver dysfunction, kidney dysfunction, thyroid abnormalities, or hypervitaminosis A. Caution is required in those with a history of mental illness or symptoms of depression; if symptoms worsen, immediate consultation with a healthcare professional is necessary. Common side effects during the treatment may include headaches, dry skin, chapped lips, flushing, increased triglycerides and cholesterol; if symptoms are severe, dosage adjustment or discontinuation may be required. Excessive exposure to ultraviolet light should be avoided, and sunscreen may be used as necessary; vigorous exercise should be avoided. If dryness of the eyes or changes in vision occur, inform the physician immediately; wearing glasses is recommended as contact lenses may be difficult to wear. This medication should not be shared with others, and blood donation should be avoided during treatment and for a certain period afterward. The medication should be swallowed with water either with or immediately after meals, and it must be stored in a cool place out of the reach of children and away from direct sunlight.

• Headache
• erythema
• flushing
• increased triglycerides
• increased cholesterol
• decreased thyroid-stimulating hormone
• decreased free T4
• anemia
• increased iron-binding capacity
• decreased monocytes

This medication is sensitive to light and must be stored in a container that blocks light. Additionally, it is important to store it in a cool place at a temperature below 30 degrees Celsius to maintain its efficacy.

Appearance

A reddish-brown oval soft capsule containing yellowish oily content.

Package unit

30 capsules/box [(10 capsules/PTP*3)]