Olveca Duo Tablets 5/20 mg

Adult dose

This medication is taken once a day as one tablet with water, regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). Administer 5/20 mg for patients whose blood pressure is inadequately controlled with monotherapy of amlodipine 5 mg or olmesartan medoxomil 20 mg. Administer 10/20 mg for patients whose blood pressure is inadequately controlled with olmesartan medoxomil 20 mg monotherapy.

Child dose

The safety and efficacy in pediatric patients under 18 years of age have not been established.

This drug can cause serious harm or death to the fetus and newborn if administered to pregnant women during the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. This drug should not be used by individuals who are allergic to the active ingredients or similar substances, pregnant or breastfeeding women, patients with severe liver dysfunction, patients with severe aortic stenosis, patients with biliary obstruction, patients on dialysis, patients in shock, certain diabetic patients, and those with severe kidney impairment. Patients with hypotension due to low fluid or sodium levels may exhibit signs of hypotension, so their condition should be closely monitored before administration. Because of the vasodilatory effect, acute hypotension may occur, so caution is needed. It should also be used cautiously in patients with severe heart disease or reduced kidney function and liver dysfunction, as this drug may affect kidney function and regular kidney function tests are recommended. During treatment, side effects such as dizziness, headache, hypotension, orthostatic hypotension, nausea, vomiting, dyspepsia, rash, and edema may occur, and if any abnormal symptoms appear, consultation with healthcare personnel should be sought immediately. This drug may interact with other medications, especially potassium-sparing diuretics, potassium supplements, lithium, and non-steroidal anti-inflammatory drugs, so caution is advised. It is also recommended to avoid grapefruit juice. This drug should not be taken during pregnancy and if planning or currently pregnant, consultation with a doctor is essential. Breastfeeding can allow this drug to pass into breast milk, potentially causing abnormal reactions in the infant, so either breastfeeding should be discontinued or the use of this drug should be stopped. Safety and efficacy in children under 18 have not been established, thus it is not recommended. In elderly patients, drug metabolism may slow down due to reduced kidney and liver function, so start with a low dose and take with caution. In cases of overdose, severe hypotension and symptoms due to vasodilation may occur, requiring immediate medical attention for appropriate treatment. This drug should be kept away from direct sunlight and moisture and stored out of reach of children, and it is advisable not to transfer it to another container.

Serious side effects

Urticaria, severe swelling (edema), difficulty breathing, severe allergic reactions, severe skin reactions, liver dysfunction (jaundice), serious neurological symptoms, markedly decreased urine output, severe edema accompanied by elevated blood pressure, acute renal failure, increased blood creatinine, angioedema.

Mild side effects

• Dizziness
• headache
• drowsiness
• sensory disturbances
• decreased sensation
• palpitations
• rapid heartbeat
• hypotension
• orthostatic hypotension
• cough

This medication may be sensitive to air or moisture, so it must be stored in a sealed container. It should also be kept at room temperature, ideally between 1 to 30 degrees Celsius.

Appearance

White round film-coated tablets

Package unit

30 tablets/PTP [(10 tablets/PTP x 3)]