Glipizide 4 mg Tablet (Glimepiride)

Adult dose

Adjust individually for each patient. Administer 1 time a day orally, swallowed without chewing with more than 1/2 cup of water. It should be taken before breakfast or right before the first meal, and it is important not to skip meals after taking the medication. For monotherapy, the initial dose is started at 1 mg once daily, and can be increased by 1 mg every 1-2 weeks. Generally, there is little additional effect from doses over 4 mg.

This medication should not be administered to patients with insulin-dependent diabetes mellitus, diabetic ketoacidosis, or those in a coma. Patients with allergies to this medication or its ingredients, or to sulfonylureas or sulfonamides should not use it. Patients with severely impaired liver or kidney function should avoid this medication and consider switching to insulin therapy. Women who are pregnant or may become pregnant, as well as those who are breastfeeding, should not take this medication. Patients with severe infections, pre- and post-surgery, or with major trauma should also consider insulin therapy. In cases of gastrointestinal disorders such as diarrhea or vomiting, nutritional absorption may be impaired, increasing the risk of hypoglycemia. During the first week of taking this medication, the risk of hypoglycemia is higher, so frequent blood glucose monitoring and careful observation is essential. Particularly, patients with poor nutritional status, those who skip meals, irregular eating patterns, excessive exercise, unbalanced carbohydrate intake, alcohol consumers, patients with impaired kidney or liver function, and the elderly are at greater risk of hypoglycemia and should be administered this medication carefully. Overdosing may lead to hypoglycemia; therefore, dosage must be strictly followed, and if hypoglycemic symptoms appear, glucose should be consumed immediately. Hypoglycemia symptoms may include headache, severe hunger, nausea, fatigue, drowsiness, confusion, shaking, dizziness, etc., so caution is advised. This medication can cause various side effects such as liver dysfunction, blood disorders, allergic reactions, and any unusual symptoms should be reported to a doctor or pharmacist immediately. Moreover, interactions may occur when taken with other medications, so inform healthcare professionals about any concurrent medications. During the course of taking this medication, maintaining a regular diet, exercise, and weight management is essential, and continuous monitoring of blood sugar levels is necessary. There is a risk of accidents due to hypoglycemia when driving or operating machinery, so caution is advised if symptoms occur. Pregnant or nursing women should not use this medication and must consider switching to insulin therapy if needed, as safety has not been established for children under 18 years of age. Elderly patients often have decreased kidney function, so dosage adjustments should be considered, and in case of overdose, they should quickly seek appropriate medical treatment.

Serious side effects

Hives, severe swelling (edema), serious allergic reactions, chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by fever, blisters, peeling skin, pain in oral/ocular mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough + fever, jaundice (yellowing of skin or eyes), extreme lethargy, liver dysfunction (jaundice), and sudden severe symptoms.

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggression
• decreased concentration
• diminished agility or motivation

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, ideally at room temperature between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness and safety.

Appearance

Light blue, oblong tablet

Package unit

For domestic use - 30 tablets/bottle, For domestic use - 500 tablets/bottle