Medication info

Raparon Tablets (Limaprost Alfadex)

Prescription medicationTablet
Ingredient · strength
Limaprost Alfadex›166.67μg / 1 tablet
Manufacturer / importer
Y.S. Life Science Co., Ltd.
Appearance
White round tablets
Packaging
84 tablets/box [21 tablets/PTP (Alu-alu) x 4]
Approval status
Active

MFDS item code 202002695 · Approved 2020.04.17

Summary

Main use
Improvement of symptoms and walking ability in lumbar spinal stenosis, and ischemic symptoms of Buerger's disease
Who uses it
Adults
Adult dosage
1. For improvement of ischemic symptoms such as ulcers, pain, and coldness due to thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally 3 times daily. 2. For improvement of subjective symptoms (lower limb pain and numbness) and walking ability due to acquired lumbar spinal stenosis (in patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. The dose may be adjusted appropriately according to age and symptoms.

Ingredients

Manufacturer
Y.S. Life Science Co., Ltd.

Efficacy & effects

Improvement of symptoms and walking ability in lumbar spinal stenosis, and ischemic symptoms of Buerger's disease

  • Ulcers
  • pain
  • cold sensation
  • leg pain
  • leg numbness
View approved original text

This medication helps improve ischemic symptoms such as ulcers, pain, and cold sensations caused by obliterative thromboangiitis. It also alleviates leg pain and numbness associated with acquired lumbar spinal stenosis and enhances walking ability. Therefore, this medication is used for the relief of symptoms and improvement of function related to vascular and nerve issues.

Dosage and Administration

Adult dosage

1. For improvement of ischemic symptoms such as ulcers, pain, and coldness due to thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally 3 times daily. 2. For improvement of subjective symptoms (lower limb pain and numbness) and walking ability due to acquired lumbar spinal stenosis (in patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. The dose may be adjusted appropriately according to age and symptoms.

Precautions

This medication should not be used by pregnant women or women who may become pregnant. This medication contains lactose, so individuals with inherited conditions that impair lactose digestion should avoid taking it. Patients at risk of bleeding or those taking medications that affect blood coagulation should use this medication with caution. While taking this medication, hypersensitivity reactions such as skin rash or itching may occur, so if these symptoms appear, discontinue use immediately. Bleeding can occur rarely, so if bleeding symptoms appear, stop taking the medication and consult a doctor. Gastrointestinal symptoms such as diarrhea, nausea, abdominal pain, decreased appetite, and heartburn may occur. Liver function abnormalities may arise, so it is advisable to periodically check liver health status. Rarely, symptoms such as increased heart rate or low blood pressure may occur, so caution is required. Various symptoms including headache, facial flushing, dizziness, and a feeling of warmth may appear, and in severe cases, consultation with a doctor is necessary. Patients with lumbar spinal stenosis should monitor symptom changes to decide whether to continue taking this medication. Safety during pregnancy has not been established, and uterine contractions have been reported in animal studies, so pregnant women should avoid taking it. Safety has not been established for children, so its use is not recommended in this population. Elderly patients may have decreased body functions, so dosage adjustments and care are needed.

Side effects

  • Rash
  • itching
  • bleeding
  • diarrhea
  • nausea
  • abdominal discomfort
  • abdominal pain
  • loss of appetite
  • heartburn
  • vomiting
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  • abdominal bloating
  • elevated AST (GOT)
  • elevated ALT (GPT)
  • palpitations
  • peripheral cyanosis
  • hypotension
  • headache
  • facial flushing
  • dizziness
  • warmth
  • generalized fatigue
  • edema
  • mastitis
  • tremors
  • hirsutism
  • anemia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain storage temperatures between 1°C and 30°C to preserve the effectiveness and safety of the medication.

Appearance and packaging

Appearance

White round tablets

Package unit

84 tablets/box [21 tablets/PTP (Alu-alu) x 4]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.