Crestin Tablet 5 mg (Rosuvastatin Calcium)

Adult dosage

This can be taken at any time during the day, regardless of meals. The initial dose is 5 mg once daily, and the maintenance dose may be adjusted up to 10 mg once daily as needed. The maintenance dose should be adjusted appropriately based on LDL-cholesterol levels, treatment goals, and patient response with an interval of 4 weeks or more, and may be increased to a maximum of 20 mg daily.

Children's dosage

For pediatric patients aged 10 to 17 years, the dose is 5 mg to 20 mg once daily. The dose should be adjusted based on the individual patient’s treatment goals, and dose adjustments should occur every 4 weeks or more.

This medication should not be used in certain patients. For instance, patients who are allergic to this medication, those with severely impaired liver function, patients with muscle disorders, severely impaired kidney function, pregnant or breastfeeding women, and women of childbearing age who do not use effective birth control should not take this medication. Periodic monitoring of liver function and muscle status is necessary while using this medication. Patients with a history of liver disease or excessive alcohol consumption require extra caution. If symptoms such as myalgia or muscle weakness occur, consult a doctor immediately and discontinue use in severe cases. This medication can increase blood sugar levels in some patients, necessitating careful blood glucose management for those at high risk for diabetes. Moreover, patients with kidney or thyroid dysfunction, elderly patients, or those who abuse alcohol are at higher risk for muscle-related side effects, so a consultation with a physician prior to treatment is warranted. This medication may interact with several other drugs; therefore, if you are currently taking any medications, it is crucial to inform your healthcare professional. Specifically, combined use with certain antiviral agents, immunosuppressants, some antibiotics, and fibrate medications may increase the risk of muscle damage. This medication is to be avoided during pregnancy or breastfeeding as it could harm the fetus or infant; women planning to become pregnant should use appropriate contraception. In the case of overdose, there is no specific antidote, so it is essential to seek appropriate treatment and monitoring at a hospital immediately. This medication does not significantly affect driving or operating machinery, but caution is advised as dizziness may occur. Lastly, if skin rash, severe muscle pain, jaundice symptoms, etc., occur while taking this medication, consult a healthcare professional immediately.

Serious side effects

Hives, hypersensitivity reactions including angioedema, Stevens-Johnson syndrome, eosinophilia with systemic symptoms drug rash (DRESS), rhabdomyolysis, severe muscle weakness, ocular myasthenia, jaundice, hepatitis, severe allergic reactions, severe skin reactions, severe edema, fatal and non-fatal liver failure, acute kidney failure, oliguria, dyspnea, respiratory issues accompanied by cough and fever

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. The appropriate storage temperature is between 1 to 30 degrees Celsius.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets (15 tablets/PTP x 2)