Artpen Injection (Acetaminophen)

Adult administration

Adults weighing over 50 kg: Administer 1000 mg of acetaminophen four times a day. Minimum dosing interval is 4 hours. Maximum daily dose is not to exceed 4 grams. Children over 33 kg and adults weighing under 50 kg: Administer acetaminophen at approximately 15 mg/kg per dose. Minimum dosing interval is 4 hours. Maximum daily dose is 60 mg/kg or not exceeding 4 grams. Severe renal impairment.

Child administration

Children weighing over 33 kg (approximately 11 years old): Administer acetaminophen at approximately 15 mg/kg per dose. Minimum dosing interval is 4 hours. Maximum daily dose is 60 mg/kg or not exceeding 4 grams.

This medication must not be confused between milligrams and milliliters during administration. Confusion between units can lead to overdose, resulting in severe poisoning or death. Once oral medications can be taken, it is advisable to use appropriate analgesics as soon as possible. Check if other medications contain the active ingredient of this drug to avoid overdose. Exceeding the recommended dosage can cause serious liver damage, so the dosage must be strictly adhered to. Symptoms of liver damage can appear between 2 to 6 days after administration, necessitating prompt treatment. Patients with compromised liver function should consult a doctor before taking this medicine, and regular liver function tests are required if taking high doses for a prolonged period. Individuals who consume alcohol daily should consult a doctor or pharmacist before taking this medication; otherwise, they are at higher risk of liver damage. Severe rashes or allergic reactions on the skin may occur in very rare cases, so if skin rashes or other hypersensitivity reactions develop, stop taking the medication immediately and consult healthcare personnel. This medication should not be used if there is an allergy to it, or if there are peptic ulcers, severe liver, kidney, or heart disorders, or if specific medications are being taken. Patients with liver or kidney issues, the elderly, pregnant women, and breastfeeding mothers should use this drug cautiously and follow a doctor’s instructions. While taking this medication, rare side effects like hypotension, liver function abnormalities, blood cell reductions, neurological disorders, skin rashes may occur. Since this drug may interact with other medications, be sure to inform healthcare personnel of any currently taken medications, especially antibiotics or anticoagulants, when using this drug together. It does not affect driving or machinery operation, but this drug should not be mixed with other medications. Children or the elderly should take the minimum effective dose and be monitored for adverse reactions closely. It is known that the use of this medication during pregnancy is relatively safe; however, it should only be taken after assessing the benefits and risks in consultation with a doctor. During breastfeeding, a small amount may be excreted in breast milk, but there have been no reports of adverse reactions, hence it can be used. Patients with severely impaired kidney function may have delayed excretion of this medication, necessitating increased dosing intervals. In case of overdose, symptoms such as nausea, vomiting, loss of appetite, abdominal pain may occur, and in severe cases, liver damage or unconsciousness may result, necessitating immediate hospital care. This medication should not be stored at temperatures above 30 degrees Celsius, and refrigeration or freezing should be avoided, checking for foreign substances or discoloration before administration. Any unused solution should be discarded.

Serious side effects

• Urticaria
• severe swelling (edema)
• anaphylactic shock
• anaphylaxis
• shock
• acute generalized pustular rash
• toxic epidermal necrolysis
• Stevens-Johnson syndrome
• fulminant hepatitis
• liver necrosis

Mild side effects

Fatigue, hypotension, increased liver transaminase levels, neurological disorders, injection site reactions (pain, burning sensation), thrombocytopenia, tachycardia, nausea, vomiting, erythema, flushing, itching, rash, urticaria, high anion gap metabolic acidosis, dizziness, decreased hemoglobin, urinary disorders.

This medication should be stored at room temperature between 1 and 30 degrees Celsius, and it is important to keep it in a sealed container to prevent air or moisture from entering. Storing it this way will maintain the drug’s efficacy and safety.

Appearance

A clear, light yellow transparent liquid filled in a colorless transparent plastic container for injection.

Package unit

100 milliliters/box