Cipra Tablet 40mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids like water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 1 time over 4 weeks - If esophagitis is untreated or symptoms persist, take for an additional 4 weeks - Maintenance therapy to prevent recurrence of esophagitis: 20 mg once daily for 1 time - Symptomatic treatment in gastroesophageal reflux disease without esophagitis: 1 time of 20 mg once daily.

Children's dosage

Adolescents aged 12 and older: - Treatment of erosive esophagitis: 40 mg once daily for 1 time over 4 weeks - Symptomatic treatment in gastroesophageal reflux disease without esophagitis: 20 mg once daily for 1 time - Symptoms.

This medication should not be administered to certain patients. It should not be used in patients who are hypersensitive to this drug, its ingredients, or benzimidazole derivatives or have a history of such reactions. Patients with hypersensitivity to antibiotics like amoxicillin or clarithromycin used in combination to eradicate Helicobacter pylori should also not take this medication. Administration is prohibited in certain patients including those on specific heart-related medications or antiviral agents, breastfeeding women, and patients with myocardial infarction. Various adverse reactions may occur when using this medication. Commonly reported side effects include headaches, abdominal pain, diarrhea, constipation, and drowsiness; less frequently, blood abnormalities, allergic reactions, liver dysfunction, skin rashes, and muscle pain may be observed. Particularly, hypomagnesemia may rarely occur, which can cause serious electrolyte imbalances, requiring caution. This medication increases the risk of bacterial infections in the stomach due to its action of suppressing gastric acid secretion. Moreover, long-term use may increase the risk of fractures, so patients at risk for osteoporosis require regular monitoring. Attention should be paid to drug interactions during medication use. In particular, when combined with digoxin, warfarin, methotrexate, antiviral agents, and certain antibiotics, there might be adverse effects due to changes in drug concentrations, so consultation with healthcare professionals is needed. There is limited safety data on this drug during pregnancy, so caution is advised when administering it to pregnant women; breastfeeding women are recommended not to take this medication. In cases of overdose, since no specific antidote exists, symptomatic treatment is required, and this medication has a high protein binding rate, which is not removed by dialysis. This medication should be kept out of reach of children, and transferring it to another container should be avoided for maintaining quality and safety.

Serious side effects

Hives, angioedema, anaphylactic reactions, shock, Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis, Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS syndrome), liver failure, encephalopathy, liver abnormalities (including hepatitis with or without jaundice), severe hypomagnesemia, rhabdomyolysis, severe allergic reactions, severe skin adverse reactions.

Mild side effects

• Headache
• dizziness
• paresthesia
• drowsiness
• taste disturbances
• blurred vision
• bronchospasm
• abdominal pain
• constipation
• diarrhea

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and must be kept at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication for a longer period.

Appearance

Pink round film-coated tablet

Package unit

28 tablets/PTP [14 tablets/Alu-Alu×2]