Rapugrine 10 mg (Ranitidine)

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is lafutidine 10mg orally twice daily, in the morning and at bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may occasionally vary from patient to patient. 2. Short-term treatment of duodenal ulcers: The usual dose is lafutidine 10mg orally twice daily, in the morning and at bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may occasionally vary from patient to patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is lafutidine 10mg orally once daily at bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks, although the healing period may occasionally vary from patient to patient. 4. Antibiotic combination therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 days or 14 days. 5. Premedication before anesthesia: The usual dose is lafutidine 10mg orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg orally twice.

This drug should not be used in patients who are allergic to any of its components. Additionally, since it contains lactose, patients with genetic lactose intolerance, lactase deficiency, or glucose-galactose malabsorption should refrain from taking it. Patients with a history of drug hypersensitivity or those with liver or kidney issues, patients undergoing dialysis, and the elderly should use this medication with caution. This medication can cause severe allergic reactions similar to anaphylaxis, so if symptoms such as facial pallor, low blood pressure, and difficulty breathing occur, stop using it immediately and seek appropriate treatment. Liver dysfunction or jaundice may occur, requiring regular liver function tests, and treatment should be stopped if abnormalities are found. There may be a risk of agranulocytosis or thrombocytopenia, so be alert for initial symptoms such as pharyngodynia, general malaise, and fever. Severe side effects such as skin rashes, convulsions, and heart block have also been reported, so consult medical personnel if any unusual symptoms occur. Common side effects may include constipation, diarrhea, hard stools, nausea, vomiting, abdominal bloating, loss of appetite, headache, insomnia, drowsiness, reversible confusion, hallucinations, consciousness disorders, dizziness, chills, heat sensation, facial flushing, increased white blood cell count, eosinophilia, decreased white blood cell count, decreased red blood cell count, decreased hematocrit, increased LDH, increased TTT, abnormal urine protein, increased BUN, increased serum uric acid, increased Cl, delayed menstruation, increased Na, decreased K, gynecomastia, edema, malaise. In particular, patients suspected of having gastric ulcers or malignant tumors should be careful as symptom relief from this drug may delay diagnosis. The elderly may exhibit decreased physical function, so dosage and administration intervals should be adjusted and used cautiously. Patients undergoing dialysis may have increased plasma drug concentrations, so it should be initiated at a lower dose and used carefully. Pregnant women or women of childbearing potential should only use it when the physician determines that the benefits of treatment outweigh the risks, and it is advisable for breastfeeding women not to take this drug. Safety in children has not been sufficiently established, so caution is advised in its use. This medication should be kept out of reach of children and stored in its original container to prevent misuse or quality deterioration.

• Shock
• symptoms of anaphylaxis
• facial pallor
• hypotension
• generalized rash
• dyspnea
• liver function impairment
• jaundice
• agranulocytosis
• pharyngitis

This medicine must be stored in a closed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. This will help preserve the effectiveness and safety of the medication for a longer duration.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle