Dabist Tablet (Metformin Hydrochloride)

Adult dosage

The dosage should be determined based on individual drug efficacy and tolerance, without exceeding the recommended maximum daily dose. This medication should be started at a low dose to minimize gastrointestinal adverse reactions while confirming the minimum effective dose needed for adequate blood sugar control, administered 2-3 times daily, with 500 mg taken with meals. Doses can be gradually increased by 500 mg weekly until reaching 20

Children's dosage

This medication can be used in children over 10 years old or adolescents during growth. The general initial dosage is 500 mg once daily, administered during or after meals. After one week, measure blood sugar levels

This medication may cause severe lactic acidosis or hypoglycemia, requiring caution. It should not be administered to patients with moderate to severe renal impairment or acute conditions such as dehydration, severe infections, cardiovascular collapse, acute myocardial infarction, or sepsis. Patients with acute heart failure or those receiving intravenous radiographic iodine contrast agents should also not use this medication, and administration should be paused for a certain period before and after contrast testing. Use is prohibited for patients with allergic reactions to this medication or biguanide drugs, or a history of type 1 diabetes, lactic acidosis, or diabetic ketoacidosis. In patients with severe infections, serious traumatic systemic disorders, pre- and post-surgery, malnutrition, liver dysfunction, pulmonary embolism, or severe pulmonary dysfunction, administration should be temporarily halted or avoided. Caution is required in patients with irregular meals, inadequate food intake, vigorous exercise, or taking interacting drugs, as there is a risk of lactic acidosis and hypoglycemia. Lactic acidosis is very rare but can be fatal, so if symptoms occur, immediately discontinue use and consult healthcare professionals. Gastrointestinal symptoms such as diarrhea, nausea, and vomiting may commonly occur during initial treatment, but they usually disappear over time. This medication is primarily excreted through the kidneys; therefore, regular kidney function tests should be performed, and if renal function declines, discontinuation or dose adjustment may be necessary. Alcohol can affect the metabolism of this medication; excessive alcohol consumption should be avoided. Vitamin B12 deficiency may occur, so regular blood tests are recommended. During pregnancy, since it crosses the placenta, fetal growth monitoring is necessary, and use should be avoided in certain pregnancy conditions. If breastfeeding, this medication is excreted in breast milk, so careful consideration regarding the continuation of breastfeeding or treatment is required. Elderly patients may have a risk of decreased renal function, thus dose adjustment and regular monitoring of renal function are necessary. This medication may interact with various drugs; therefore, consultation with healthcare professionals regarding concomitant medications is advised. In cases of overdose, blood dialysis may be beneficial, so seek immediate medical attention. This medication does not cause weight gain, thus favorably assisting in weight management, and may help in blood sugar control and reduction of diabetes-related complications with long-term use. Store out of reach of children, and avoid transferring to another container.

Serious side effects

Lactic acidosis (acute renal function deterioration, metabolic complications associated with cardiopulmonary diseases, sepsis), severe allergic reactions (such as rash), serious neurological symptoms (severe headache, confusion), liver abnormalities (possible jaundice due to liver dysfunction), hypoglycemia (severe delayed hypoglycemia), significant edema and urinary abnormalities (severe swelling, decreased renal function), respiratory problems (if shortness of breath occurs)

Mild side effects

Gastrointestinal symptoms (diarrhea, nausea, vomiting, abdominal distension, loss of appetite, indigestion, constipation, abdominal pain), unpleasant or metallic taste, rash, anemia, leukopenia, thrombocytopenia, vitamin B12 deficiency, abnormal liver function, hypoglycemia, failure to control blood sugar, etc.

This medication should be stored in a sealed container to prevent air or moisture ingress. It is recommended to keep the medication at room temperature, between 1°C and 30°C, not too hot or too cold.

Appearance

White round film-coated tablets

Package unit

500 tablets/bottle