Megapibatine Tablet 2 mg (Pitavastatin Calcium)

Adult dose

For adults, the usual initial dose of pitavastatin calcium is 1 to 2 mg once daily. If the LDL cholesterol lowering effect is insufficient, it may be increased up to a maximum of 4 mg daily. The dose should be adjusted appropriately every 4 weeks or longer based on LDL cholesterol levels, therapeutic goals, and patient response.

This medication should not be used in patients with allergies to specific ingredients or who have liver function issues. It may be risky to take for patients with active liver disease or consistently elevated liver enzymes, as well as those with severe liver impairment or bile duct obstruction. Patients taking cyclosporine or those with myopathy, pregnant or possibly pregnant women, breastfeeding women, and children should not be given this medication. Patients with renal dysfunction or a history of liver issues should use this medication cautiously, especially if used with fibrate medications or niacin, as there may be risks of muscle damage and worsening renal function. Older adults may also experience adverse reactions more readily when taking this medication. Adverse reactions such as myalgia, weakness, skin rash, itching, dyspepsia may occur when taking this medication, and rhabdomyolysis, where muscle tissue breaks down, can occur rarely; if symptoms of muscle pain or weakness appear, medical consultation should be sought immediately. Liver dysfunction, thrombocytopenia, allergic reactions, etc. may also occur, necessitating regular blood tests and liver function tests. As this medication is used to treat hyperlipidemia, it is essential to check blood lipid levels before administration and conduct regular tests during administration to evaluate the treatment's effectiveness. Patients with weak liver function may require dose adjustments and regular liver function tests must be performed during treatment. This medication can interact with other drugs, so caution is especially needed when taken with cyclosporine, fibrate medications, niacin, or erythromycin, and if symptoms like myalgia or weakness occur during combined usage, administration should be stopped immediately. This medication is not used in pregnant or breastfeeding individuals, and if pregnancy is confirmed, administration should be stopped immediately. Its safety and efficacy in children have not been established, so it is not used in pediatric patients. This medication should be kept out of reach of children and stored in its original container. Older adults and those with renal or liver dysfunction are at increased risk of adverse reactions and should take this medication with caution.

Serious side effects

• Hives
• severe swelling (edema)
• chest tightness
• difficulty breathing
• rhabdomyolysis
• myopathy
• liver dysfunction
• jaundice
• thrombocytopenia
• severe allergic reactions

Mild side effects

• Abdominal pain
• rash
• fatigue
• numbness
• itching
• headache
• stiffness
• dizziness
• thirst
• dyspepsia

This medication should be stored in a tightly closed container that can block light, at a temperature between 1 and 30 degrees Celsius. Proper storage ensures the medication's effectiveness is maintained and prevents degradation.

Appearance

Very light yellowish-red, round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle