Limaprost Tablet 5 Micrograms (Limaprost Alpha-Dex)

Adult dose

For improvement of ischemic symptoms such as ulcers, pain, and coldness associated with thromboangiitis obliterans (Buerger disease), the usual adult dose is 2 tablets orally 3 times daily. For improvement of subjective symptoms (lower-limb pain and numbness) and walking ability associated with acquired lumbar spinal canal stenosis (in patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. Adjust the dose as appropriate according to age and symptoms.

This drug should not be used in women who are pregnant or may become pregnant. Additionally, since it contains lactose, it should not be administered to patients with genetic problems such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. It should be used cautiously in patients with a tendency to bleed or those taking antiplatelet agents, thrombolytics, or anticoagulants. When using this medication, hypersensitivity reactions such as rashes or itching may occur, and if these symptoms appear, use should be immediately discontinued. Bleeding may occur rarely; thus, symptoms should be closely monitored, and if abnormal signs appear, administration should be stopped. Gastrointestinal side effects may include diarrhea, nausea, abdominal discomfort, abdominal pain, loss of appetite, and heartburn. Since it may affect liver function, it is advisable to regularly check whether liver enzyme levels are elevated. Cardiovascular abnormalities such as palpitations or cyanosis of the extremities and low blood pressure may also occur rarely. Various other side effects such as headaches, facial flushing or dizziness, heat sensation, tremors, edema, and anemia may also occur. In patients with lumbar spinal stenosis, it is important to carefully observe symptoms and decide whether to continue using the drug. Safety in pregnancy has not been established, and uterine contractions have been reported in animal studies, so it should not be administered to pregnant women. Safety in children has also not been confirmed, so it is advisable not to use it in children. Elderly patients may experience decreased physical function, so caution is needed, such as adjusting the dose of the medication. Lastly, if a large dose is administered to healthy adults, transient hypotension may occur, so caution is warranted.

• Rash
• itching
• bleeding
• diarrhea
• nausea
• abdominal discomfort
• abdominal pain
• loss of appetite
• heartburn
• vomiting

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is advisable to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance

White round tablet

Package unit

84 tablets/PTP [84 tablets/Alu-Alu ((21 tablets/Alu-Alu) x 4)]