Allfenacin Tablets 5mg (Solifenacin Succinate)

Adult dose

The usual recommended dose for adults (including elderly patients) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This drug may be taken with or without food and should be swallowed whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment No dosage adjustment is required for patients with mild or moderate renal impairment (creatinine clearance>30ml/min). For patients with severe renal impairment (creatinine clearance≤30ml/min), administer with caution and do not exceed 5mg once daily. 2. Patients with hepatic impairment No dosage adjustment is required for patients with mild hepatic impairment. For patients with moderate hepatic impairment (Child-Pugh class B), administer with caution and do not exceed 5mg once daily. 3. Patients receiving potent cytochrome P450 3A4 (CYP3A4) inhibitors For patients receiving ketoconazole or another potent CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication should not be used in patients with certain diseases or conditions. For example, it should not be administered to patients who have difficulty urinating, severe gastrointestinal diseases, myasthenia gravis, glaucoma, patients allergic to this medication, patients undergoing dialysis, and patients with severe liver or kidney dysfunction. Additionally, caution should be exercised when administering this medication to patients at risk of urinary retention, with a risk of gastrointestinal obstruction or decreased gastrointestinal motility, those with severe kidney or liver dysfunction, and those taking specific medications concomitantly. While taking this medication, side effects such as dry mouth, constipation, blurred vision, urinary retention may occur, and some patients may experience severe gastrointestinal issues. In case of severe symptoms due to side effects, patients are advised to consult their healthcare provider. This medication may cause serious allergic reactions such as arrhythmias or angioedema, or anaphylaxis, and should be discontinued immediately and treated if these symptoms occur. This medication may have increased effects or aggravated side effects when taken with other anticholinergic medications, so patients should inform their healthcare provider of all medications currently being taken. Also, as this medication is metabolized in the liver, dose adjustments may be necessary for patients with impaired liver function or those taking specific medications. Women who are pregnant or breastfeeding should use caution with this medication, as its safety has not been established, and especially during breastfeeding, it is recommended to avoid use. The safety and efficacy of this medication have not been confirmed in children, hence it should not be used in this population. In case of an overdose, patients should visit a medical facility immediately for appropriate treatment, and it is advised to administer activated charcoal and treat symptoms rather than inducing vomiting. During treatment with this medication, patients should be careful while driving or operating machinery, as drowsiness or blurred vision may occur.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colon obstruction
• intestinal obstruction
• vascular neurogenic edema
• nausea

This medication should be stored in a sealed container to prevent exposure to air, and the storage temperature should be maintained between 1 degree and 30 degrees Celsius at room temperature. This will help maintain the medication's efficacy and safety for a longer duration.

Appearance

Bright yellow round film-coated tablets

Package unit

100 tablets (10 tablets/PTP*10)