Itraconazole Tablets (Itraconazole Solid Dispersion)

Adult dosage

Administration immediately after a meal is preferred to increase the absorption of this medicine. 1) Candidal vaginitis: Administer itraconazole 200 mg twice daily (morning and evening) for 1 day, or 200 mg once daily for 3 days. 2) Pityriasis versicolor: Administer 200 mg once daily for 7 days. 3) Tinea corporis and tinea cruris: Administer 100 mg once daily for 15 days. 4) Tinea manuum (interdigital type) and tinea pedis (interdigital type): Administer 100 mg once daily for 15 days. 5) Tinea manuum (palmar) and tinea pedis (plantar): Administer 100 mg once daily for 30 days, or 200 mg twice daily for 7 days. 6) Oral candidiasis: Administer 100 mg once daily for 15 days. 7) Fungal keratitis: Administer 200 mg once daily for 21 days. Administer 200 mg per dose twice daily for 1 week, followed by a 3-week drug-free period; this constitutes 1 cycle. Administer up to 2 cycles for infection limited to the fingernails, and up to 3 cycles for infection of the toenails. Affected area of onychomycosis Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Toenails (with or without concomitant fingernail infection) Treatment Drug-free period Treatment Drug-free period Treatment Fingernails Treatment Drug-free period Treatment Or Administer 200 mg once daily for 3 months. The therapeutic effect continues for 3 months for fingernails and 6 months for toenails after completion of treatment. In patients with impaired immune function, such as those with neutropenia, AIDS, or organ transplantation, the oral bioavailability of this medicine may be reduced; if necessary, the dose should be doubled. Aspergillosis: 200mg once daily; average treatment duration 2～5 months. For invasive or disseminated disease, increase to 200mg twice daily. Candidiasis: 100～200mg once daily; average treatment duration 3 weeks～7 months. Cryptococcal meningitis: 200mg twice daily; average treatment duration 2 months～1 year. Maintenance therapy: 200mg once daily. Paracoccidioidomycosis: 100mg once daily; average treatment duration 6 months.

This medication should not be administered to patients with reduced cardiac function or a history of heart failure. If symptoms of heart failure appear during treatment, administration should be stopped immediately. This medication can cause severe side effects when taken with certain drugs, so it should not be used with contraindicated medications. Patients who have had allergic reactions to this medication or its components should also avoid taking it. Pregnant women or women of childbearing potential, as well as nursing mothers, should not use this medication and effective contraceptive methods should be employed after use. This medication contains lactose, so patients with lactose intolerance should avoid taking it. Patients with poor liver or kidney function should consult a physician before use, and dosage adjustments may be necessary. This medication has many interactions with various drugs, so it is essential to inform healthcare providers of any other medications being taken. Regular monitoring of liver function tests and heart status should be performed during treatment to identify any abnormalities. Symptoms such as dizziness, headaches, indigestion, rash, changes in hearing may occur, and if any unusual symptoms arise, it is important to inform healthcare providers immediately. There are no specific antidotes in case of overdose, and treatment will be based on the symptoms. Finally, keep this medication out of the reach of children and store it in the original container for safe use.

headache, nausea, abdominal pain, rhinitis, sinusitis, upper respiratory infection, leukopenia, hypersensitivity, taste disturbance, sensory impairment, altered sensation, tinnitus, constipation, diarrhea, dyspepsia, bloating, vomiting, liver dysfunction, hyperbilirubinemia, itching, rash, urticaria, polyuria, erectile dysfunction, menstrual disorders, edema, granulocytopenia, thrombocytopenia, anaphylactoid reaction, hyperglycemia, hyperkalemia, hypokalemia, hypomagnesemia, confusion, peripheral neuropathy, dizziness, drowsiness, tremors, heart failure, left ventricular failure, tachycardia, hypertension, hypotension, pulmonary edema, speech disorder, cough, gastrointestinal disorders, liver failure, hepatitis, jaundice, erythematous rash, hyperhidrosis, myalgia, arthralgia, renal disorders, urinary incontinence, generalized edema, facial edema, chest pain, fever, pain, fatigue, chills, leukocytosis, eosinophilia, anemia, vascular edema, serum sickness, angioedema, anaphylaxis, anaphylactic shock, allergic reaction, diplopia, visual impairment, hearing loss, ventricular extrasystole, atrioventricular block, palpitations, increased intestinal motility, belching, glossitis, stomatitis, abdominal and lower back pain, pancreatitis, increased total serum protein, elevated total bilirubin, increased LAP, loss of appetite, fatigue, brown urine, increased liver enzyme levels, mucous membrane syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, Leal syndrome, erythema multiforme, hair loss, photosensitivity reaction, exfoliative dermatitis, leukocytoclastic vasculitis, acute generalized exanthematous pustulosis, elevated BUN, positive urine protein, positive urine glucose, reduced libido, drowsiness, shoulder stiffness, insomnia, chest pain, elevated serum triglycerides, burning sensation, elevated serum uric acid, elevated serum potassium levels, serum sickness, angioedema, anaphylactic reactions, hypertriglyceridemia, tremors, visual impairment, transient hearing loss, permanent hearing loss, congestive heart failure, dyspnea, pancreatitis, serious hepatotoxicity, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, erythema multiforme, exfoliative dermatitis, leukocytoclastic vasculitis, hair loss, photosensitivity, increased serum creatine phosphokinase activity

Store this medication in a tightly closed container to prevent air and moisture from entering, at room temperature between 1°C and 30°C. Proper storage helps maintain the effectiveness of the medication.

Appearance

White or yellowish round film-coated tablet

Package unit

28 tablets/bottle, 100 tablets/bottle