Lirone Tablet 35 mg (Sodium Risedronate)

Adult dose

Adults: Administer 35 mg of risedronate sodium orally once weekly. Elderly (over 60 years): No dose adjustment is necessary. Patients with creatinine clearance of 30 mL/min or more: No dose adjustment is necessary. This medicine is contraindicated in patients with severe renal impairment and creatinine clearance below 30 mL/min. Food interferes with the absorption of this medicine. For adequate absorption, take it at least 30 minutes before breakfast or at least 2 hours before or after food or beverages at any other time of day. Take this medicine in an upright position with plenty of plain water (170 ∼ 230 mL) to help it reach the stomach easily and reduce the possibility of esophageal irritation. Taking this medicine with any other beverage, including mineral water, may reduce its absorption. Do not chew or suck this medicine because of the possibility of oropharyngeal ulceration. Patients should not lie down for at least 30 minutes after taking it. If a patient forgets to take this medicine on the scheduled day, take it the next morning when remembered. Resume taking it on the originally scheduled day for the next dose. Do not take 2 tablets on the same day.

Child dose

Children under 18 years of age: Safety and efficacy have not been established.

This medicine may irritate the stomach and esophagus, so caution is required for those with upper gastrointestinal conditions such as gastritis, esophagitis, and ulcers. Patients with esophageal problems or difficulty swallowing should consult a doctor before taking this medicine. Take this medication with a sufficient amount of water, and do not lie down for at least 30 minutes after taking it. It should be taken at least 30 minutes before meals or at a time separated from meals. This medicine may cause serious esophageal adverse reactions such as esophagitis, esophageal ulcers, and esophageal erosion, so if symptoms occur, stop taking it immediately and consult a doctor. Patients with certain diseases, pregnant or breastfeeding women, and patients with severe kidney dysfunction should not take this medication. This medicine contains lactose, so patients with lactose intolerance should not take it. Long-term use may lead to rare side effects such as osteonecrosis of the jaw and atypical fractures, so regular check-ups and following doctor's instructions are necessary. Taking it along with drugs or foods containing calcium, magnesium, iron, etc. may interfere with the absorption of this medication, so it should be taken at separate times. During pregnancy, this medication may affect the fetus, so women who might become pregnant should consult a doctor before taking it. Safety in children and adolescents under 18 has not been established. The elderly show a similar safety profile to that of adults, but caution is needed when taking it. An overdose may cause hypocalcemia, requiring emergency treatment, and if any abnormal symptoms appear after taking, inform medical personnel immediately. This medication should be stored out of reach of children and it is advisable not to transfer it to another container. Read the product information thoroughly before taking and always follow the instructions of your doctor or pharmacist.

• Esophagitis
• esophageal ulcer
• esophageal erosion
• esophageal obstruction
• esophageal perforation
• bleeding
• infection
• low back pain
• accidental injury
• pain

This medication should be stored in a tightly closed container to avoid exposure to air or moisture, and it is best kept at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medicine for a longer period.

Appearance

Pale orange round film-coated tablet

Package unit

4 tablets/PTP