Ar-En Tablets (Ebastine)

Adult dose

1. Asthma, urticaria, eczema, dermatitis, itchy skin, pruritic rash (prurigo), and common psoriasis accompanied by itching Adults: The usual dose is 20 mg of epinastine hydrochloride orally once daily. Adjust the dose as appropriate according to symptoms. 2. Allergic rhinitis Adults: The usual dose is 10–20 mg of this medicine orally once daily. Adjust the dose as appropriate according to symptoms.

This medication should not be administered to patients with a hypersensitivity to this drug or its components. It contains lactose, so it should not be used in patients with genetic problems such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. Administer this drug cautiously in patients with liver disease or a history of liver disease, as there is a risk of worsening liver conditions. If any allergic reactions such as rashes, urticaria, redness, itching, or swelling occur during treatment, discontinue use immediately and seek appropriate medical attention. Caution is advised as psychiatric symptoms such as drowsiness, fatigue, headache, dizziness, insomnia, nightmares, numbness, and a feeling of mental fog may occur. Gastrointestinal issues such as nausea, abdominal discomfort, dry mouth, abdominal pain, loss of appetite, vomiting, diarrhea, constipation, dry lips, abdominal bloating, and stomatitis may occur. Liver function abnormalities may appear, so liver function tests and symptom observation are necessary; patients with hepatitis or existing liver damage should be monitored for symptom worsening. Rarely, abnormal kidney function may cause proteinuria, requiring observation. Urinary symptoms such as frequent urination, hematuria, and urinary retention may also occur; discontinue use if any abnormal symptoms appear. Cardiovascular symptoms such as palpitations may occur, so caution is advised. Respiratory issues such as dyspnea, difficulty in expectoration, and nasal congestion may rarely occur. Hematologic abnormalities such as thrombocytopenia or leukocytosis have been reported; proper treatment is necessary if abnormal symptoms arise. Gynecomastia, breast enlargement, menstrual irregularities, flushing, bitter taste, taste reduction, and chest pain may rarely occur. This drug does not provide rapid relief from asthma attacks, so patients with asthma should be adequately informed. Patients receiving prolonged steroid therapy should manage a gradual tapering of steroids when using this drug. This medication can cause drowsiness, so caution is required when operating machinery or driving. If effects are not confirmed, caution should be taken to avoid long-term use. Seasonal allergy patients are advised to start taking the medication before symptoms appear and to continue during the symptom period. This drug has minimal interactions with other medications, but caution is necessary when combined with sedatives or alcohol. Pregnant women or those who may become pregnant should consider the benefits and risks of treatment carefully, and breastfeeding women should avoid use or discontinue breastfeeding. Safety in children, especially in preterm infants or newborns, has not been sufficiently confirmed. Elderly patients commonly have reduced liver and kidney function, so careful observation for adverse reactions is essential, and dosage adjustments may be necessary. In case of overdose, cardiac issues such as arrhythmias may occur, requiring ECG monitoring and symptomatic treatment. This medicine should be kept out of reach of children and should not be transferred to other containers. Taking this medication on an empty stomach may increase blood concentration, so it is recommended to take it before or after meals depending on the condition.

Allergic reactions (rash, hives, redness), itching, swelling (face, limbs, etc.), redness accompanied by itching, drowsiness, lethargy, headache, dizziness, insomnia, nightmares, numbness, feeling of heaviness in the head, nausea, discomfort in the stomach, dry mouth, abdominal pain, loss of appetite, vomiting, feeling of pressure in the stomach, feeling of fullness, diarrhea, constipation, dry lips, abdominal bloating, stomatitis, liver dysfunction, jaundice, hepatitis, worsening symptoms, proteinuria, increased urination, hematuria, urinary retention, palpitations, shortness of breath, difficulty in expectoration, nasal congestion, thrombocytopenia, leukocytosis, gynecomastia, breast enlargement, abnormal menstruation, flushing, bitter taste, decreased taste sensitivity, chest pain

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Moreover, the storage temperature should be maintained between 1 to 30 degrees Celsius at room temperature. Storing it this way helps to preserve the drug's efficacy for a longer duration.

Appearance

This medicine is a white or off-white, round film-coated tablet.

Package unit

30 tablets/bottle, 100 tablets/bottle