DROVAN (Ibandronic Acid Sodium Hydrate)

Adult administration

Administer 3 mg by intravenous injection every 3 months for 15 - 30 seconds.

This medication must only be administered by intravenous injection, and caution is necessary because incorrect injection around arteries or veins can cause tissue damage. It should not be used in patients with allergies to this medication or its ingredients, or in patients with untreated hypocalcemia. During the use of this medication, various side effects such as gastritis, diarrhea, abdominal pain, indigestion, nausea, constipation, muscle pain, joint pain, fatigue, headache, rash, etc., may occur, but most are mild to moderate and not severe enough to require discontinuation of treatment. Rarely, osteonecrosis of the jaw, external auditory canal osteonecrosis, serious allergic reactions, ocular inflammation, atypical fractures, etc., have been reported, necessitating caution. Patients requiring dental treatment should undergo oral examination before administration and avoid excessive dental procedures while receiving this medication. This medication can temporarily lower blood calcium levels, so it is important to treat hypocalcemia and bone and mineral metabolism disorders before administration and to ensure sufficient intake of calcium and vitamin D. Patients with impaired kidney function or those taking medications that may affect the kidneys require regular monitoring and examination. Pregnant or breastfeeding women are advised not to use this medication due to the lack of safety confirmation. In cases of overdose, there may be toxicity to the kidneys and liver, which requires careful monitoring and appropriate treatment. This medication should not be mixed with calcium-containing solutions or other intravenous medications and must be administered solely by intravenous injection. Do not reuse the needle and syringe after use; dispose of them safely.

Serious side effects

Hives, angioedema, facial swelling/edema, anaphylactic reaction/shock, asthma exacerbation, Stevens-Johnson syndrome, erythema multiforme, bullous dermatitis, osteonecrosis (jaw and external auditory canal), acute renal failure, multiple organ failure, death, respiratory distress, vascular anomalies, severe allergic reactions, severe skin adverse reactions, severe bone, joint, and/or muscle pain, atypical femoral fractures, atypical fractures, fractures, optic nerve atrophy, tremors, hyperventilation

Mild side effects

• Gastritis
• diarrhea
• abdominal pain
• indigestion
• nausea
• constipation
• musculoskeletal pain
• joint pain
• muscle pain
• influenza-like illness

This medication should be stored in a sealed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

A colorless and transparent solution contained in a colorless and transparent glass prefilled syringe with an attached single-use needle.

Package unit

3 milliliters/prefilled syringe