Famotidine 20 mg Tablets

Adult dosage

For oral administration, for gastric/duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, Zollinger-Ellison syndrome: 20 mg of famotidine is taken orally twice a day (after breakfast, after dinner, or at bedtime) or 40 mg once a day (at bedtime). In the case of upper gastrointestinal bleeding, treatment should be initiated with the injectable form and switched to oral administration when possible. For gastric mucosal lesions (acute gastritis, acute exacerbation of chronic gastritis): Adults should take 10 mg of famotidine orally twice a day (after meals or at bedtime) or 20 mg once a day (at bedtime). Dosage should be adjusted according to age and symptoms. (Injection) Adults: Famotidine 20 mg is dissolved in 20 mL of normal saline solution or glucose solution and slowly administered intravenously twice a day (every 12 hours) or mixed into an infusion. Typically, the effect appears within one week for upper gastrointestinal bleeding and Zollinger-Ellison syndrome, and oral administration should be switched when possible. For use as pre-anesthetic medication, 20 mg should be dissolved in 1-1.5 mL of injection water and administered intramuscularly one hour before anesthesia induction, or slowly administered intravenously one hour before anesthesia induction. After dissolving, it should be used within 48 hours if stored at room temperature or refrigerated. Dosage should be adjusted according to age and symptoms.

This medication should not be used in patients who have had allergic reactions to its components or other H2 receptor antagonists. Additionally, this medication contains lactose, and should not be administered to patients with a hereditary condition that affects lactose digestion. Patients with a history of drug allergies, reduced kidney function, heart disease, liver dysfunction, and the elderly should use this medication with caution. While taking this medication, serious adverse reactions may occur including severe allergic reactions, blood disorders, skin disorders, liver dysfunction, muscle damage, cardiac arrhythmias, altered consciousness, kidney problems, pneumonia, etc. Therefore, symptoms should be carefully monitored. If any of these serious symptoms occur, discontinue the medication immediately and seek medical treatment. Common side effects may include rash, urticaria, changes in blood counts, dyspepsia, changes in blood pressure, respiratory issues, liver dysfunction, neuropsychiatric symptoms, hormonal changes, and arthralgia; if these symptoms occur, consult a doctor. During treatment, it is important to carefully monitor the patient's condition and only use the minimum effective dose; if there is no effectiveness, switch to alternative treatment methods. This medication dissolves in the mouth but is not absorbed through the oral mucosa, so it must be swallowed with water or saliva. Patients receiving hemodialysis should be cautious when using this medication combined with phosphate binders as it may reduce the effectiveness of calcium preparations. This medication may interact with certain antifungals or some anticancer drugs, possibly reducing their effectiveness, so inform your doctor or pharmacist of any other medications you are taking. Elderly patients may have increased blood concentration of this medication due to reduced kidney function, thus dosage should be reduced or the dose interval increased for cautious use. Women who are pregnant or may become pregnant should only use this medication when the potential benefits outweigh the risks, and breastfeeding women should discontinue nursing if using this medication. Safety has not been sufficiently established for pediatric use, so caution is advised. Finally, this medication may mask symptoms of stomach cancer, so it should only be used when it is assured that cancer is not present.

Serious side effects

Shock, hypersensitivity (anaphylaxis, dyspnea, generalized erythema, angioedema, urticaria), aplastic anemia, agranulocytosis, hemolytic anemia, thrombocytopenia, Stevens-Johnson syndrome, Lyell syndrome, liver dysfunction, jaundice, rhabdomyolysis, QT prolongation, ventricular tachycardia, ventricular fibrillation, altered consciousness, seizures, interstitial nephritis, acute renal failure, interstitial pneumonia, contraction failure.

Mild side effects

• Rash
• urticaria (erythema)
• facial edema
• constipation
• diarrhea
• dry mouth
• nausea
• vomiting
• abdominal bloating
• loss of appetite

This medication should be stored in a tightly sealed container to prevent air ingress, and it is recommended to store it at room temperature between 1 degree Celsius and 30 degrees Celsius. Proper storage can help maintain the medication's efficacy.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle, 1000 tablets/bottle