Lesta Tablet 5 mg (Rosuvastatin Calcium)

Adult dosage

Regardless of meals, the initial dose of 5 mg is administered once daily at any time of the day. If necessary, the maintenance dose can be adjusted to 10 mg once daily. The dose can be increased up to 20 mg once daily at intervals of 4 weeks or more based on LDL cholesterol levels and patient response. For Asian patients and those susceptible to myopathy, the recommended initial dose is 5 mg; a dose of 40 mg is contraindicated.

Children's dosage

For pediatric patients aged 10 to 17 years with heterozygous familial hypercholesterolemia, the dosage is 5 mg to 20 mg once daily. The dosage is adjusted according to individual treatment goals over a period of 4 weeks.

This medicine should not be administered to certain patients. Those who are allergic to this medicine or have liver function issues, those with muscle disease, those with severely impaired kidney function, and women who are pregnant or breastfeeding should not take this medicine. Additionally, as this medicine contains lactose, caution is needed for those who are lactose intolerant. Before taking this medicine, regular liver function tests and muscle-related tests should be performed, and those with conditions such as hypothyroidism or nephrotic syndrome need to be treated first. If symptoms like myalgia or muscle weakness appear, consult a doctor immediately, and if symptoms are severe, discontinue use. This medicine should be used cautiously in those who consume excessive alcohol or have a history of liver disease. Moreover, this medicine can interact with other drugs, so it is essential to inform the doctor of all medications currently being taken, especially that the risk of muscle damage may increase when taken with fibrate medications. This medicine can rarely cause severe skin reactions or liver damage; thus, if symptoms like rash or jaundice occur, stop taking the medicine immediately and inform a doctor. Women who could become pregnant should use adequate contraception, and this medicine should not be taken during pregnancy. There are no specific antidotes for overdose, so treatment should be based on symptoms, and liver function and muscle enzyme levels should be monitored. Dizziness may occur while driving or operating machinery, so caution is needed. Regular tests and management per doctor's instructions during the course of this medicine are essential.

Serious side effects

Urticaria, hypersensitivity reactions including angioedema, severe allergic reactions; Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), severe skin adverse reactions; rhabdomyolysis, severe myopathy, muscle disease; respiratory distress, interstitial lung disease related to dyspnea, asthma exacerbation; jaundice, hepatitis, fatal and non-fatal liver failure, liver abnormalities; severe muscle weakness, ocular myasthenia, immune-mediated

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medicine should be stored in a tightly closed container to protect it from exposure to air and moisture, and it is safest to store it at a temperature between 1 and 30 degrees Celsius. Proper storage maintains the effectiveness of the medicine and prevents deterioration.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle