Clopidogrel Tablets (Clopidogrel Hydrogen sulfate)

Adult dosage

1. For patients with ischemic stroke, myocardial infarction, or peripheral arterial disease, administer clopidogrel 75 mg orally once daily. 2. For patients with acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction), start treatment on the first day with a loading dose of 300 mg of this medicine once daily, followed by a maintenance dose of 75 mg orally once daily. Aspirin 75 ～ 325 mg should be administered once daily in combination with this medicine. 3. For patients with atrial fibrillation, administer 75 mg of this medicine orally once daily. Aspirin 75 ～ 100 mg should be administered once daily in combination with this medicine. This medicine may be administered with or without food.

This medication is used to prevent platelets from aggregating, thereby inhibiting blood clotting. The effectiveness may be reduced in individuals genetically predisposed to certain enzyme deficiencies, in which case alternative treatment options should be considered. Moreover, caution should be exercised when taking this drug with other medications that activate certain enzymes, as it may increase drug concentration and elevate bleeding risk. Patients with allergies to this medication, severe bleeding, very poor liver function, women who are breastfeeding, and those with lactose intolerance should not take this medication. Patients at high risk of bleeding or those scheduled for surgery should consult a physician before taking this medication, and if bleeding symptoms occur, they should immediately inform the hospital. The risk of bleeding may increase when this medication is taken in conjunction with other anticoagulant drugs, so caution is necessary when used together. During treatment, bleeding may take longer to stop, so it is essential to inform the physician about taking this medication during trauma or surgery. This drug can rarely cause serious side effects, such as a sudden drop in platelet count; therefore, if fever or signs of infection appear, immediate consultation with medical staff is required. Gastrointestinal disorders, diarrhea, headaches, and rashes may occur as side effects, and immediate treatment should be sought if severe bleeding symptoms develop. No effects on the fetus have been reported during pregnancy; however, caution is needed due to the risk of bleeding during delivery. In breastfeeding, since this medication may pass into breast milk, careful consideration should be given to whether to continue taking the medication and breastfeeding. Elderly patients or those with impaired kidney and liver function may be at higher risk of bleeding, thus requiring dosage adjustment and monitoring. Overdosage may increase the risk of bleeding, and since there are no specific antidotes, treatment such as platelet transfusion may be necessary in case of bleeding. This drug should be stored out of reach of children and it is advisable not to transfer it to another container.

• Hemorrhage
• gastrointestinal bleeding
• purpura
• contusion
• hematoma
• epistaxis
• hematoma
• hematuria
• intraocular hemorrhage
• intracranial hemorrhage

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is essential to maintain a storage temperature between 1 and 30 degrees Celsius to preserve the drug's efficacy and safety for an extended period.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle