Genupharm Prucalopride Tablets 2 mg (Prucalopride Succinate)

Adult dose

This medication is administered orally and may be taken at any time of day, regardless of meals. Adults should take 2 mg once daily. For elderly patients aged 65 and older, the initial dose is 1 mg once daily, which can be increased to 2 mg once daily if necessary. For patients with severe kidney impairment (GFR < 30 ml/min/1.73 m2) and severe liver impairment (Child-Pugh class C), the dosage is 1

This medication should not be used in certain patients. For example, people who are allergic to the active ingredient or excipients, patients with severely impaired kidney function, those with serious intestinal problems, and individuals with genetic issues such as lactose intolerance should not be administered this medication. Additionally, patients with greatly reduced kidney function should use it with caution and at a reduced dose; similar caution applies to patients with other serious conditions such as liver or heart disease. Those with a history of cardiac arrhythmias or ischemic cardiovascular diseases should be especially careful. Common gastrointestinal symptoms such as headache, abdominal pain, nausea, and diarrhea may occur when taking this medication, typically appearing early in treatment and resolving over time. Rarely, symptoms like palpitations, fatigue, or dizziness may arise, and patients should consult a doctor if these symptoms develop. The possibility of drug interactions is relatively low, but caution is needed when taken with certain medications. It is particularly important to be careful when used in conjunction with drugs that can prolong the QTc interval, and the drug concentrations may be altered when combined with some antifungal or heart-related medications. The use of this medication is not recommended during pregnancy, and women of childbearing potential should use effective contraceptive measures while taking it. Nursing mothers should avoid using this medication as it can be excreted in breast milk. It is safest not to administer this medication to children or adolescents under 18 years of age. In case of overdose, symptoms such as headache, nausea, or diarrhea may appear; treatment should be symptomatic. If there is significant fluid loss through diarrhea or vomiting, electrolyte replacement may be necessary. This medication may cause dizziness or fatigue upon initial use, so caution is advised when driving or operating machinery. Finally, this medication should be kept out of reach of children and stored in its original container, protected from moisture.

Serious side effects

Chest discomfort, ventricular extrasystole

Mild side effects

• Headache
• dizziness
• tremors
• palpitations
• nausea
• diarrhea
• abdominal pain
• vomiting
• dyspepsia
• rectal bleeding

This medication should be protected from light and moisture and stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Pink round film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu×2)