Montelukast Sodium 4 mg (Montelukast Sodium)

Adult dose

Adults and adolescents aged 15 and above should take Montelukast 10 mg orally once daily. This medication is taken once a day, preferably in the evening for asthma patients. It should be administered 1 hour before or 2 hours after meals.

Child dose

Children aged 6 to 14 years should take Montelukast 5 mg once daily, by chewing or placing on the tongue to dissolve, with no water. Additionally, a 5 mg dry syrup should be administered orally once daily, using one sachet in a cup.

This medication should not be administered to patients with the genetic disorder phenylketonuria, as the artificial sweetener aspartame contained in this medication is broken down into phenylalanine in the body, which can be harmful to patients with phenylketonuria. Additionally, this medication contains lactose and should not be used by patients with genetic issues such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. This medication is not for the treatment of acute asthma attacks; therefore, appropriate rescue medications must always be available during an acute asthma attack. While taking this medication, do not suddenly stop or switch inhaled or oral corticosteroids without medical guidance; dosages should be adjusted gradually according to a doctor's instructions. Furthermore, neuropsychiatric symptoms (e.g., anxiety, depression, hallucinations) may occur while taking this medication, so it is important to immediately report any such symptoms to your doctor. Do not use this medication alone for the treatment of exercise-induced bronchospasm; continue using inhaled β-agonists if necessary, and always have a rapid-acting inhaler on hand. Patients with aspirin hypersensitivity should not take aspirin or non-steroidal anti-inflammatory drugs concurrently with this medication. Rarely, patients with asthma taking this medication may experience systemic eosinophilia and vasculitis symptoms, hence careful monitoring for eosinophilia, skin rashes, worsening respiratory symptoms, and cardiac complications is essential. This medication has not been reported to cause increased adverse reactions when used with other asthma prevention and treatment medications; however, caution is warranted when taken with specific liver enzyme-inducing medications. Pregnant women should only use this medication if clearly necessary, and breastfeeding mothers should be cautious as this medication can be excreted in breast milk. Caution is advised when using this medication in children, especially in infants under 6 months of age, as safety and efficacy have not been established. In cases of overdose, there is no specific antidote, so general symptomatic treatment and clinical monitoring are necessary, and it is crucial to take this medication immediately after opening due to its sensitivity to light. Finally, this medication should be taken consistently even when asthma symptoms are absent, and if symptoms worsen or adverse reactions occur, consult a doctor immediately.

Serious side effects

Hives, toxic epidermal necrolysis, Stevens-Johnson syndrome, angioedema, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanying cough and fever, yellowing of the skin or eyes, extreme fatigue, sudden and severe headache, thunderclap headache, seizures

Mild side effects

• Weakness/fatigue
• fever
• abdominal pain
• dyspepsia
• infectious gastroenteritis
• toothache
• dizziness
• headache
• nasal congestion
• cough

This medication is sensitive to moisture and light, so it should be stored at room temperature between 1°C and 30°C. It is also important to keep the medication in a tightly sealed container to prevent exposure to air.

Appearance

Homogeneous white granules without impurities

Package unit

30 sachets/box [(500 mg/sachet)]