Mega Cetirizine Tablet (Levocetirizine Hydrochloride)

Adult dose

Adults and children over 6 years: take 1 tablet (Levocetirizine Hydrochloride 5 mg) orally once daily, regardless of meals. Adjust as appropriate according to age and symptoms. Patients with kidney impairment should adjust their dosage based on kidney function (creatinine clearance rate - CLCR). Dosage and frequency based on creatinine clearance rate: - Mild (50 ≤ CLCR < 80): 1 tablet once daily - Moderate (30 ≤

Child dose

Children over 6 years: take 1 tablet (Levocetirizine Hydrochloride 5 mg) orally once daily, regardless of meals.

This medicine should not be used by individuals with allergies to certain components or those hypersensitive to hydroxyzine or piperazine derivatives. It should also not be administered to patients with severely impaired kidney function or those undergoing hemodialysis. It is safer for pregnant or potentially pregnant women and nursing mothers to avoid this medication. It should not be used in infants under 1 year of age, and liquid forms should be given to children under 6 years rather than tablets. Patients with lactose intolerance or genetic lactose enzyme deficiency should avoid taking this medicine due to its lactose content. Patients with weak kidney or liver function, as well as the elderly, should use it cautiously as the drug can remain in the body for a longer time. Taking this medicine can cause side effects such as drowsiness, headache, and dizziness, so caution should be exercised when driving or operating machinery. Taking it with alcohol or central nervous system depressants can increase drowsiness, so it is advised not to take them together. Patients at risk of urinary retention should consult a doctor before administration. This medicine should not be taken with other antihistamines while consuming excessive alcohol, and there may be interactions with some medications, so it is important to inform about other medications being taken. Pregnant and nursing individuals should avoid this medication, particularly during breastfeeding due to the possibility of excretion into breast milk. The dosage for children under 12 years should be carefully adjusted, and it is not to be used in infants under 1 year of age. Elderly patients may experience increased drug concentration due to decreased kidney function, so it is necessary to start with a lower dose and monitor their condition. It is recommended to discontinue this medication before allergy testing as it may affect the results. In cases of overdose, symptoms such as drowsiness or agitation may occur, and there are no specific antidotes, hence appropriate treatment according to the symptoms should be administered. This medicine cannot be effectively removed through hemodialysis.

Serious side effects

• Urticaria, edema, angioedema, anaphylactic shock → severe allergic reaction
• Rash, severe rash with high fever, blisters, peeling skin → severe skin abnormal reaction
• Shortness of breath, bronchospasm → respiratory issues
• Hepatitis, increased AST, ALT, Al-P, total bilirubin → liver abnormalities (jaundice)
• Severe headache, seizures, suicidal thoughts, syncope, tremors, dizziness → serious neurological symptoms
• Urinary retention, urination difficulties, edema,

Mild side effects

• Drowsiness
• lethargy
• headache
• numbness
• fatigue
• dizziness
• heavy feeling in the head
• excitement
• thirst
• dry lips

This medicine is sensitive to light and should be stored in a container that protects it from light. Additionally, it is best stored at room temperature, between 1 and 30 degrees Celsius. Storing it this way will help maintain the drug's effectiveness.

Appearance

White or yellowish oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle