Yuhan Three Chamber Forms Protect Injection

Adult administration

Children over 12 years and adults - For normal nutritional status or mild metabolic stress: 0.6-0.9 g/kg of amino acids per day (0.10-0.15 g/kg of nitrogen) - For moderate to severe metabolic stress: 0.9-1.6 g/kg of amino acids per day (0.15-0.25 g/kg of nitrogen) Dosage: 20-40 mL/kg per day (Amino acids 0.6-1

Child administration

Children aged 2-11 years Dosage: Administer up to 40 mL/kg per day, adjusted regularly Administration rate: Do not exceed 3.0 mL/kg per hour Recommended administration period: 12-24 hours Minimum administration period

This medication should only be used under the direction of a physician. If symptoms of allergic reactions such as fever, chills, rash, or difficulty breathing occur during use, administration should be stopped immediately. Precipitation may occur when used with intravenous calcium-containing preparations, thus this medication and calcium preparations should not be administered simultaneously using the same infusion device, and the infusion line should be thoroughly cleaned before and after administration. Caution is required in premature or low-birth-weight infants due to the risk of increased plasma free fatty acid levels, especially in premature infants with severe respiratory diseases, where fatal cases have been reported after administering this medication. Patients with allergies to fish, eggs, soy, peanuts, or certain diseases such as severe hyperlipidemia, liver dysfunction, blood coagulation disorders, amino acid metabolism disorders, severe renal failure, acute shock, and uncontrolled hyperglycemia should not be administered this medication. In renal failure, diabetes, hepatic dysfunction, hypothyroidism, and sepsis, lipid metabolism disorders may occur, and careful administration is needed. During administration, blood triglyceride levels should be regularly monitored to ensure they do not exceed 4 mmol/L, as overdose may result in lipogenic syndromes, amino acid excess, or hyperglycemia. This medication contains soybean oil, fish oil, and egg yolk lipids, which may rarely cause allergic reactions, hence caution is advised for patients with a history of allergies. During administration, strict aseptic techniques must be followed to reduce the risk of infections, and the intravenous injection site should be checked daily for signs of thrombophlebitis or other complications. During pregnancy or breastfeeding, safety has not been established, thus it should only be administered when the therapeutic benefits outweigh the risks. In the case of overdose, the infusion rate should be immediately reduced or stopped, and treatment such as insulin administration or dialysis may be necessary.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, fever, chills, rash, respiratory distress, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output, severe body swelling accompanied by increased blood pressure, anaphylactic reactions, severe allergic reactions

Mild side effects

Loss of appetite, nausea, vomiting, increased plasma liver enzyme levels, thrombophlebitis, hypotension, hypertension, mild increase in body temperature, chills, headache, dizziness, skin rash, flushing, warmth, coldness, pain (in the neck, back, bones, chest, or waist), hyperglycemia, nausea, vomiting, sweating, body temperature increase, constipation, diarrhea, indigestion, swelling, generalized weakness, hypoglycemia, increased urination, vein inflammation, extravasation at the infusion site, chest discomfort, runny nose, visual disturbances

This medication should be stored in a sealed container to prevent air or moisture ingress. It should be kept at a cool temperature below 25 degrees and should not be frozen.

Appearance

This medication consists of a plastic packaging designed for intravenous fluids, divided into three chambers, with an oxygen absorber placed in between. Each inner chamber contains Dextrose solution.

Package unit

For infusion - 362 milliliters/bag [Solution A 197mL, Solution B 114mL, Solution C 51mL], For infusion - 952 milliliters/bag [Solution A 518mL, Solution B 300mL, Solution C 134mL], For infusion - 1206 milliliters/bag [Solution A 656mL, Solution B 380mL, Solution C 170mL], For infusion - 1448 milliliters/bag [Solution A 788mL, Solution B 456mL, Solution C 204mL]