Gliporin Tablets 2/500 milligrams

Adult dose

This medication is administered 1 to 2 times daily before meals or with meals. The dosage may be adjusted based on each patient's current treatment regimen, effectiveness, and tolerance, and proper blood sugar monitoring should be conducted. Typically, treatment is initiated at a low dose, adjusting according to the patient's current medications and blood sugar levels. In clinical trials, the initial daily dose was glimepiride/metformin hydrochloride 2mg/500mg.

This medication carries the risk of severe lactic acidosis or hypoglycemia, and should be discontinued if kidney function declines sharply. It is advisable to temporarily stop this medication and consult a physician in the presence of symptoms of dehydration, severe diarrhea, vomiting, or fever. Avoid using this medicine in patients with impaired kidney function or liver dysfunction; extra caution is required, especially in the elderly or with other medications that may affect kidney function. Patients with cardiovascular disease or a history of myocardial infarction should also be cautious when taking this medication. Women who are pregnant or breastfeeding should not take this medicine; switching to insulin therapy is recommended if necessary. This medication can cause hypoglycemia, especially if meals are missed or nutritional status is poor, so it is important to take it with meals and monitor symptoms carefully. Alcohol consumption can increase the risk of lactic acidosis, so it is important to avoid excessive drinking while taking this medication. Regular blood sugar and kidney function, liver function, and hematological tests should be conducted to check for abnormalities during treatment with this medication. Interactions with other drugs may occur, so it is essential to consult a physician or pharmacist when starting or stopping new medications. In case of overdose, severe hypoglycemia or lactic acidosis may occur, and immediate medical attention should be sought. Caution is needed when driving or operating machinery as hypoglycemic symptoms may pose risks. This medication has not been sufficiently proven safe and effective for children, so caution should be exercised in usage.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, lactic acidosis, hypoglycemia, liver dysfunction (elevated liver enzymes, liver damage, jaundice, hepatitis), severe allergic reactions, thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, agranulocytosis, pancytopenia, thrombocytopenic purpura, deep vein thrombosis, cardiac arrest, brain convulsions due to hypoglycemia, loss of consciousness, coma, paralysis, confusion, visual impairment

Mild side effects

Gastrointestinal symptoms (diarrhea, nausea, vomiting, abdominal bloating, loss of appetite, indigestion, constipation, abdominal pain), unpleasant or metallic taste, visual impairment, erythema, itching, rash, nausea, vomiting, upper abdominal fullness, pressure, abdominal pain, dizziness, palpitations, light-headedness, abdominal bloating, indigestion, prostatic enlargement, leg edema, facial swelling, erectile dysfunction, hair loss, facial flushing, gastritis

Store this medication in a tightly closed container to prevent air and moisture ingress, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for a longer period.

Appearance

White oblong film-coated tablet

Package unit

Domestic use - 30 tablets/bottle, Domestic use - 100 tablets/bottle