Clarinol 250 mg (Clarithromycin)

Adult dosage

Adults The usual dose of clarithromycin is 250mg (potency) per dose, twice daily; for severe infections, administer 500mg (potency) per dose, twice daily. The usual treatment duration is 7~14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer for more than 14 days to these patients. Mycobacterial infections Administer 500mg (potency) of this medication per dose, twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Helicobacter pylori eradication in patients with duodenal ulcers Administer 500mg (potency) of this medication 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1~14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and over: Same as adults. For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be administered to certain patients. For example, it should not be used by patients who are allergic to any of its components or have had allergic reactions to similar classes of antibiotics. Additionally, it should not be taken by patients with certain heart conditions or severe liver or kidney dysfunction, as well as pregnant or breastfeeding women. This medication may interact with other drugs, hence it is crucial to inform your physician or pharmacist of any other medications you are currently taking. Caution is particularly advised when taken with drugs that affect the heart or those metabolized by the liver. Various side effects such as allergic reactions, gastrointestinal disturbances, liver dysfunction, kidney dysfunction, skin rashes may occur while using this medication; immediate consultation with healthcare personnel is recommended if symptoms arise. Furthermore, this medication may lead to the development of resistant bacteria if used over long periods or repeated courses; therefore, it is important to adhere to the prescribed duration and dosage by your physician. It is safest for pregnant or breastfeeding individuals to avoid this medication and seek alternative medications through consultation with healthcare providers when necessary. Dosage adjustment may be needed for children or the elderly according to their physiological status, therefore, follow the directions of healthcare professionals. While taking this medication, one should exercise caution when driving or operating machinery as symptoms like dizziness or confusion may arise. In case of overdose, gastrointestinal disturbances or central nervous system symptoms may occur, necessitating immediate medical attention. Finally, this medication must be stored under appropriate conditions, away from children's reach.

Shock, anaphylactic symptoms, dyspnea, seizures, flushing, rash, itching, urticaria, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal erosion, epigastric pain, seizure type, dry mouth, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, abdominal pain, frequent diarrhea, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, acute sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, seizures, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, increased ALP, total bilirubin elevation, anorexia, dark urine, pruritus, abdominal tenderness, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, elevated CPK, elevated serum myoglobin, urinary myoglobin elevation, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, dysgeusia, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, tinnitus, auditory impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, purpuric rash, acute generalized pustular eruption, injection site phlebitis, injection site pain, injection site inflammation, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, urinary discoloration, vasodilation, cardiac arrest, atrial fibrillation, QT prolongation on ECG, extrasystoles, palpitations, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, rash, diaphoresis, vesicular dermatitis, papular rash, acne, Henoch-Schönlein purpura, muscle cramps, musculoskeletal stiffness, myopathy

This medication should be stored in a well-closed container to avoid exposure to air or moisture, preferably at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication for a longer time.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle