Cepharodin Capsule (Cefaclor Hydrate)

Adult dose

Administer 250mg (potency) of cefaclor hydrate every 8 hours orally. In cases of severe infections and low-sensitivity infections, the dose may be increased to twice the normal amount. In cases of acute gonococcal urethritis, administer 3g of this drug along with 1g of probenecid as a single combined treatment.

Child dose

Administer 20mg (potency) per Kg body weight every 8 hours. For severe infections, otitis media, and low-sensitivity infections, a dose of 40mg (potency) per Kg body weight may be administered, with a maximum dosage of 1.

This drug works by binding to specific proteins and inhibiting bacterial cell wall synthesis, killing the bacteria. Patients who have experienced severe allergic reactions or shock due to this drug should not use it. Additionally, those who are allergic to this drug or to cephalosporin antibiotics should avoid its use. Patients with penicillin allergies or allergic tendencies, severely impaired renal function, those who are unable to take orally, elderly patients, and patients with gastrointestinal disorders should exercise extra caution when using this drug. During the course of treatment, rare but severe allergic reactions, skin rashes, blood abnormalities, liver or kidney dysfunction, gastrointestinal issues, respiratory problems, and central nervous system abnormalities may occur, so it is important to consult a doctor immediately if symptoms arise. It is crucial to use this medication only for an appropriate duration to prevent the development of resistant bacteria. Drug interactions may occur when taken with other medications, especially those affecting the kidneys, anticoagulants, or oral contraceptives, so it’s important to inform healthcare providers of such use. Pregnant or breastfeeding women should use this drug cautiously as its safety has not been fully established, following medical advice. It is recommended not to use this drug in neonates under one month of age as its safety and efficacy have not been established. Elderly patients may experience a higher incidence of adverse reactions due to decreased bodily functions, hence dosage adjustments and monitoring are necessary. This drug may also affect certain urine test results, so it is advisable to inform healthcare providers during testing.

Serious side effects

Urticaria, severe swelling (edema), dyspnea, shock, anaphylactic symptoms (generalized flushing, swelling, difficulty breathing, angioedema, sensory disturbances, fainting, hypertension, vasodilation), Stevens-Johnson syndrome, toxic epidermal necrolysis, severe skin reactions, liver dysfunction (jaundice), reversible interstitial nephritis, acute kidney failure, severe renal impairment, pseudomembranous colitis, asthma, dyspnea, interstitial pneumonia, eosinophilic lung infiltrates, rash

Mild side effects

• Rash
• itching
• fever
• lymphadenopathy
• arthralgia
• serum sickness-like reactions
• agranulocytosis
• granulocytopenia
• anemia
• thrombocytopenia

This drug is sensitive to light and should be stored in a container that blocks light. Additionally, it should be stored at room temperature, between 1 and 30 degrees Celsius, to maintain its effectiveness and prevent degradation.

Appearance

Hard capsules with a light blue opaque upper part and a white opaque lower part filled with white or pale yellow crystalline powder.

Package unit

Oral use - 30 capsules/bottle, Oral use - 300 capsules/bottle