Donepezil 10 mg Tablets (Donepezil Hydrochloride Hydrate)

Adult dosage

As Donepezil Hydrochloride, administer 5 mg once daily before bedtime. For 4 to 6 weeks, administer the 5 mg dose, and after assessing the clinical response, it may be increased to 10 mg. When increasing to 10 mg daily, caution is advised regarding gastrointestinal side effects. The maximum dose is 10 mg.

Children's dosage

There is no experience in using this medication in children.

This medicine should not be used by patients with allergies to specific components or by women who are pregnant or breastfeeding. Patients with lactose intolerance or certain genetic disorders should also avoid this medication. Patients with heart diseases or cardiac conduction disorders need to be cautious as this medication can cause bradycardia or arrhythmia. Patients with peptic ulcers or those taking non-steroidal anti-inflammatory drugs should use this medication carefully as it can promote gastric acid secretion, worsening ulcer symptoms. Patients with a history of asthma or obstructive pulmonary disease should exercise caution as it may cause bronchial constriction or increased mucus secretion, worsening symptoms. Patients with extrapyramidal disorders such as Parkinson's disease should be careful as this medication may worsen their symptoms. Patients allergic to certain colorant ingredients should also use this medication with caution. During treatment with this medication, serious adverse reactions such as fainting, heart problems, gastrointestinal bleeding, liver function abnormalities, neurological symptoms, muscle abnormalities, and respiratory distress may occur; consult healthcare providers immediately if symptoms appear. Mild adverse reactions may include nausea, vomiting, diarrhea, dizziness, insomnia, headaches, and fatigue. This medication should only be used for the treatment of Alzheimer's type dementia and is not approved for other types of dementia or memory disorders. The therapeutic effect should be evaluated regularly, and treatment may be discontinued if there is no effect. This medication may affect heart rate; therefore, patients with heart conditions may require an ECG. Caution is needed while driving or operating machinery, especially during the initial period of treatment or dosage changes, as dizziness or muscle cramps may occur. Women who are pregnant or breastfeeding are advised against using this medication unless absolutely necessary, in which case, consultation with a healthcare professional is recommended. Safety for children has not been established; therefore, it should not be used in pediatric patients. This medication may interact with other drugs, so inform healthcare providers of any other medications being taken. In case of overdose, severe symptoms such as nausea, vomiting, respiratory depression, and muscle weakness may occur, requiring immediate emergency treatment. Keep this medication out of the reach of children, and do not transfer it to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe allergic reaction, high fever accompanied by severe rash, blisters, skin peeling, mucosal pain in the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough and fever, respiratory issues, yellowing of the skin or eyes (jaundice), pronounced lethargy, liver abnormalities (jaundice), sudden changes.

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headaches
• fatigue
• fever
• dizziness
• insomnia
• drowsiness

This medication should be stored in a tightly sealed container to prevent air or moisture from entering and kept at room temperature between 1°C and 30°C. Proper storage will maintain the efficacy and prevent deterioration of the medication.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle