Gimuradol Semi-Sustained Release Tablet

Adult dose

Initially, 2 tablets are administered, with subsequent dosing intervals of at least 12 hours. Do not exceed 8 tablets in one day and do not use for a longer period than necessary. If long-term use is necessary, regular monitoring should be conducted. For elderly patients, the adult dosage may be given, but for those over 75 years, intervals of at least 12 hours should be observed.

This medication may put a strain on the liver, so individuals who consume large amounts of alcohol daily should consult a doctor or pharmacist before taking it. Due to the acetaminophen component, there may be rare occurrences of severe skin rashes or allergic reactions; if any skin abnormalities occur, discontinue use immediately. The tramadol component can increase the risk of seizures in case of overdose, and the risk may increase when taken with certain antidepressants or other narcotic analgesics, so caution is advised. In patients with severe respiratory diseases, severe respiratory depression may occur when administered, thus it should only be given in a medical facility. This medication can cause severe drowsiness or respiratory depression when taken in combination with alcohol or benzodiazepines; thus, it is advisable not to take them together. Patients with brain injury or increased intracranial pressure should be cautious due to the risk of respiratory depression and increased intracranial pressure when taking this medication. The tramadol component can induce physical and mental dependence, so the potential for dependence should be carefully monitored with long-term use. Patients with compromised liver function may experience liver damage due to the acetaminophen component of this medication, so they must follow a doctor's prescription. In patients with a rapid genetic metabolic rate, the effects of this drug may be excessive, increasing the risk of respiratory depression, thus dosage adjustment or alternative medications may be necessary. This medication is not to be administered to children under 12 years old or adolescents under 18 who have undergone tonsillectomy or adenoidectomy. During use, electrolyte disturbances such as hyponatremia can occur; particularly elderly patients or those with risk factors should undergo blood tests to monitor their condition. Individuals with a history of allergy to this medication's components, severe respiratory depression, severe liver or kidney impairment, pregnant or nursing women, or those taking certain medications should not use this medication. This medication can cause drowsiness or dizziness, so caution is needed while driving or operating machinery. In case of overdose, severe respiratory depression or liver damage may occur, so it is crucial to adhere strictly to the prescribed dosage and visit a medical institution immediately if any suspicious symptoms arise.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mouth/eyes mucosa, shortness of breath or difficulty breathing, asthma attacks, breathing abnormalities accompanied by cough+fever, yellowing of skin or eyes (jaundice), severe drowsiness, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination changes

Mild side effects

• Weakness
• fatigue
• flushing
• rigidity
• fainting
• withdrawal symptoms
• hypertension
• worsening hypertension
• hypotension
• arrhythmia

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. Storage temperature should be maintained between 1 degree and 30 degrees Celsius, avoiding excessively hot or cold places.

Appearance

Light yellow round sustained release film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle