Acefa Injection (Acetaminophen)

Adult dosage

Adults weighing over 50 kg: Administer 1000 mg of acetaminophen intravenously 4 times a day. The minimum dosing interval is 4 hours, and the maximum daily dosage should not exceed 4 grams. Adults weighing between 33 kg and below 50 kg: On each administration, 15 mg/kg of acetaminophen should be administered via intravenous injection, with a minimum interval of 4 hours. The maximum daily dosage should not exceed 60 mg/kg or 4 grams.

Children's dosage

Children weighing 33 kg (approximately 11 years) or more: On each administration, 15 mg/kg of acetaminophen should be administered intravenously, with a minimum interval of 4 hours between doses. The maximum daily dosage is 60 mg/kg or 4 grams.

This medication must be used according to the specified dosage. Confusing milligrams (mg) and milliliters (mL) can lead to serious side effects or toxicity, so caution is required. When oral medication can be taken, it is advisable to use an appropriate analgesic straight away. If other medications are taken, it is essential to check whether those medications contain the component of this drug to avoid overdose. Exceeding the recommended dosage can cause serious liver damage, so patients with impaired liver function should take it only after consulting a doctor. Symptoms of liver damage may appear typically 2 to 6 days later, so if abnormal symptoms occur, it is necessary to visit a hospital immediately. People who consume alcohol frequently and daily should consult an expert before taking this medication, as the risk of liver damage may increase. If severe rashes, blisters, or red spots appear on the skin during the use of this medication, stop taking the drug immediately and consult a doctor. Individuals with allergies to acetaminophen or this drug, or those with peptic ulcers, severe liver or renal disorders, should not use this medication. Patients with severely compromised heart function or a history of aspirin-induced asthma should also avoid taking this medication. Precautions should be taken when using this medication in those with liver or kidney dysfunction, the elderly, pregnant women, lactating mothers, and children, and consultation with a doctor may be necessary. This medication may interact with other drugs, so it is essential to inform about any medications currently being taken, especially when used with certain antibiotics, anticonvulsants, and anticoagulants. Overdose can result in symptoms like vomiting, loss of appetite, abdominal pain, and in severe cases, liver failure and death, requiring immediate medical treatment. This medication does not affect driving or machine operation; however, it should not be mixed with other drugs. After administration, symptoms of infection may be masked, so appropriate treatment is required if infection is suspected.

Serious side effects

Urticaria, severe swelling (edema), anaphylactic shock, anaphylaxis, angioedema, systemic rash, blistering, skin peeling, pain in oral/ocular mucosa, acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, toxic epidermal necrolysis, liver abnormalities (increased levels of liver transaminases related to jaundice, fulminant hepatitis, hepatic necrosis, liver failure), coma, severe edema, increased blood pressure, agranulocytosis, neutropenia.

Mild side effects

• Fatigue
• hypotension
• increased levels of liver transaminases
• neurological disorders
• neurological comatose state
• rashes
• injection site reactions
• maculopapular rashes
• bullous eruptions
• pustular eruptions

This medication should be stored in a sealed container to avoid contact with air and kept at room temperature, ideally between 1 and 30 degrees Celsius. Proper storage helps maintain the drug’s effectiveness.

Appearance

A clear, light yellow transparent liquid filled in a colorless and transparent plastic container for injection.

Package unit

100 milliliters/pack