Retami Tablets 500 mg (Clarithromycin)

Adult dosage

○ Adults: The usual dose is 250mg (potency) of clarithromycin twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal failure whose creatinine clearance is 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this drug to these patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) of this drug twice daily. In this case, it should be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcer: Administer 500mg (potency) of this drug 3 times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Pediatric patients aged 12 years and older: same as adults For pediatric patients under 12 years of age, use clarithromycin dry syrup.

This medication should not be used in certain patients. For example, patients with allergies to any of the ingredients, those who have had hypersensitivity reactions to certain antibiotics, and patients with severe heart conditions, liver dysfunction, or severely reduced kidney function may be at risk if they take this medication. Additionally, pregnant or breastfeeding women are advised not to take this medication, as it can be excreted in breast milk and may affect the baby. When taking this medication, care should be taken regarding interactions with other medications. The risk of side effects such as heart rhythm disturbances, liver function abnormalities, and kidney problems may increase if taken with certain other drugs, so it must be discussed with a doctor or pharmacist. While taking this medication, if symptoms such as allergic reactions, breathing difficulties, severe rashes, abdominal pain, diarrhea, or dizziness occur, you should immediately stop taking the medication and inform healthcare personnel. Patients with weakened liver or kidney function, the elderly, and those with heart disease should be more cautious when using this medication, and regular check-ups to monitor their condition are important. This medication can cause hearing loss, tinnitus, muscle problems, etc., if used long-term or in excess, so the prescribed dosage and administration should be strictly followed. Lastly, this medication may affect your ability to drive or operate machinery, so caution is advised when engaging in these activities after taking it.

Shock, anaphylactic symptoms, shortness of breath, convulsions, flushing, rash, itching, hives, mild skin flushing, angioedema, joint swelling, drug rash, abdominal bloating, nausea, vomiting, dyspepsia, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal lesions, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste disorder, decreased appetite, constipation, discoloration of stool, membranous colitis, hemorrhagic colitis, fever, cough, chest X-ray abnormalities, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, acute exacerbation of acute maxillary sinusitis, leukopenia, thrombocytopenia, pancytopenia, hemolytic anemia, agranulocytosis, dizziness, depression, taste loss, smell loss, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory impairment, hypoglycemia, tinnitus, auditory impairment, purpuric rash, acute generalized exanthematous pustulosis (AGEP), muscle cramps, musculoskeletal stiffness, myopathy, elevated serum creatinine, elevated blood urea nitrogen, nephritis, venous inflammation at the injection site, pain at the injection site, inflammation at the injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color

This medication is sensitive to light and should be stored in a light-resistant, tightly sealed container. It is important to maintain a storage temperature between 15 and 30 degrees Celsius. This way, the effectiveness and safety of the medication can be well preserved.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 200 tablets/bottle