Medication info

Diclorajoo (Diclofenac beta-Dimethylaminoethanol)

Prescription medicationInjections주사
Ingredient · strength
Diclofenac Beta-Dimethylaminoethanol›45mg / 1mL
Manufacturer / importer
(주)씨엠지제약
Appearance
A transparent solution that is colorless to pale yellow in a brown ampoule
Packaging
50 ampoules/box [2mL/ampoule x 50]
Approval status
Active

MFDS item code 201907955 · Notified 2019.11.18 · Insurance code 648603941

Summary

Main use
Relief of inflammation and pain such as in rheumatoid arthritis
Who receives it
Adults
Adult administration
As Diclofenac beta-Dimethylaminoethanol, administer 90 mg deep intramuscularly on one side of the upper buttock daily. In severe cases, 90 mg may be administered twice a day, alternating injection on both buttocks. Following the initial treatment period, the dosage may be switched to tablets or suppositories. Adjust the dosage appropriately based on age, illness, and symptoms. To minimize cardiovascular adverse reactions of this medication, use the minimal effective dose for the shortest duration necessary.

Ingredients

Manufacturer
(주)씨엠지제약

Efficacy & effects

Relief of inflammation and pain such as in rheumatoid arthritis

  • Rheumatoid arthritis
  • osteoarthritis
  • ankylosing spondylitis
  • post-traumatic inflammation
  • post-surgical inflammation
  • pain
  • acute gout
  • renal colic
  • hepatic colic
View approved original text

This medication is effectively used for chronic joint diseases such as rheumatoid arthritis, osteoarthritis (degenerative joint disease), and ankylosing spondylitis. It also alleviates inflammation and pain that occurs after trauma or surgery, and aids in the treatment of acute gout as well as renal and hepatic colic symptoms. It is widely utilized for various joint and pain-related conditions, contributing to the improvement of patients' discomfort.

How it is given

Adult administration

As Diclofenac beta-Dimethylaminoethanol, administer 90 mg deep intramuscularly on one side of the upper buttock daily. In severe cases, 90 mg may be administered twice a day, alternating injection on both buttocks. Following the initial treatment period, the dosage may be switched to tablets or suppositories. Adjust the dosage appropriately based on age, illness, and symptoms. To minimize cardiovascular adverse reactions of this medication, use the minimal effective dose for the shortest duration necessary.

Precautions

Individuals who regularly consume three or more alcoholic beverages a day should consult with a doctor or pharmacist before taking this medication. Consuming alcohol while taking this medication may lead to gastrointestinal bleeding. This medication may affect the cardiovascular system and increase the risk of serious thrombotic events such as myocardial infarction or stroke. Extra caution is required for those with a history of cardiovascular disease or risk factors. Additionally, this medication carries the risk of gastrointestinal problems such as bleeding, ulcers, and perforation. Elderly patients or those with a history of gastrointestinal conditions should take caution when using this medication. In cases of severe allergic reactions, a rare allergic response called Kounis syndrome, which can induce myocardial infarction, may occur. When in an ampoule form, there is a risk of glass particle contamination, so care should be taken when breaking the ampoule, especially when used in children or the elderly. It contains benzyl alcohol, so it is advisable not to use this medication in premature infants or neonates. This medication should not be administered to patients with specific conditions such as peptic ulcers, severe blood disorders, liver or kidney impairment, hypertension, or heart failure. Those who have had allergic reactions to asthma medications or nonsteroidal anti-inflammatory drugs should not use this medication. Before taking this medication, always discuss your medical history and current health status with a doctor, especially ensuring that the minimum dosage is used with caution in elderly patients and children. While taking this medication, watch for adverse reactions such as headache, indigestion, skin rash, symptoms of liver or kidney dysfunction, and shortness of breath, and report any symptoms immediately to healthcare personnel. This medication should preferably not be used in late pregnancy as it may pose a risk to the fetus, and if breastfeeding, consideration should be given to stopping breastfeeding as it may affect the baby. Additionally, this medication may increase the risk of side effects when taken with other nonsteroidal anti-inflammatory drugs or specific medications, so discussion with a doctor or pharmacist is essential before deciding on concurrent use. In summary, this medication poses risks of cardiovascular and gastrointestinal side effects; thus, individuals with specific conditions should avoid or use it with caution. Monitor closely for any unusual symptoms during use, and individuals who are pregnant or breastfeeding should consult a specialist before using this medication.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), severe lethargy, sudden and very severe headache, thunderclap headache, seizures, disorientation, vision changes, paralysis, urinary changes

Mild side effects

  • Loss of appetite
  • nausea
  • vomiting
  • abdominal pain
  • diarrhea
  • stomatitis
  • thirst
  • constipation
  • itching
  • rash
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  • drowsiness
  • dizziness
  • insomnia
  • nervousness
  • tingling
  • confusion
  • hallucination
  • convulsions
  • blurred vision
  • tinnitus
  • increased blood pressure
  • decreased blood pressure
  • palpitations
  • tachycardia
  • general fatigue
  • sweating
  • hair loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a container that does not allow light to enter. Additionally, it is important to maintain a storage temperature between 1 degree and 30 degrees Celsius to preserve the medication's effectiveness.

Appearance and packaging

Appearance

A transparent solution that is colorless to pale yellow in a brown ampoule

Package unit

50 ampoules/box [2mL/ampoule x 50]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.