Cilecox Capsule 100 Milligrams (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be taken with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS) Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks of taking 400 mg daily, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication can increase the risk of gastrointestinal bleeding in individuals who consume a large amount of alcohol daily; it is necessary to consult a doctor or pharmacist. This medication may increase the risk of serious cardiovascular side effects, such as cardiovascular thrombotic events, myocardial infarction, and stroke, and should be used at the lowest effective dose and for the shortest duration. This medication may cause serious gastrointestinal issues such as perforation, ulcers, and bleeding; if symptoms such as epigastric pain, indigestion, black stools, or hematemesis occur while taking it, immediate medical attention is required. This medication should not be administered to individuals with specific allergies, severe liver or kidney diseases, active gastric ulcers, or to pregnant or breastfeeding women. Patients with compromised liver or kidney function, asthma, heart failure, high blood pressure, or diabetes should use this medication cautiously and consult a doctor before use. Routine checks of liver and kidney functions, blood pressure, and blood tests should be carried out during treatment to monitor for abnormalities. Various side effects such as headache, dizziness, indigestion, vomiting, skin rash, edema, hypertension, and cardiac abnormalities may occur, and any unusual symptoms should be reported to a doctor immediately. This medication may interact with other medications; it is especially important to inform a doctor if taken with antihypertensives, anticoagulants, antidepressants, or antibiotics, as dosage adjustments may be necessary. Women who are pregnant or planning to become pregnant should not take this medication, and breastfeeding women should also avoid its use or stop breastfeeding. This medication is not recommended for use in children and adolescents under 18 years of age due to unproven safety and efficacy. Elderly patients may have compromised liver, kidney, and heart functions; therefore, special care is needed when taking this medication, and dosage adjustments may be required. Dizziness or drowsiness may occur during use, so caution is advised when driving or operating machinery. It is advisable to avoid alcohol consumption while taking this medication, and if any unusual symptoms occur after use, immediate consultation with medical personnel is advised.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tracts, ulcers, hemorrhage, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle tone increase, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcers, dental diseases, duodenal ulcers, esophageal ulcers, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, headache, leg cramps, tension increase, sensory decrease, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, back pain, allergic exacerbation, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial edema, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic reaction, angioedema, loss of appetite, increased appetite, depression, neuroexcitability, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory infections, sinusitis, pharyngitis, rhinitis, bronchial spasms, exacerbated bronchial spasms, dyspnea, laryngitis, pneumonia, nosebleeds, dysphonia, vesicular dermatitis, dermatitis, nail diseases, phototoxic reactions, pruritus, erythematous rashes, maculopapular rashes, skin diseases, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, skin-mucosal syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash accompanied by eosinophilia and systemic symptoms, arrhythmia, left ventricular hypertrophy, angina pectoris, unstable angina, coronary artery disorders, myocardial infarction, heart failure, palpitations, tachycardia, stroke, aortic valve stenosis, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombotic venous disease, vasculitis, deep vein thrombosis, cerebral hemorrhage, isolation, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, mastalgia, menopausal symptoms, fibrocystic changes of the breast, thoracic neoplasia, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urinary urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, synovial bursa, arthralgia, arthropathy, skeletal anomalies, myalgia, cervical tension syndrome, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in the back, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic esophagitis, contact dermatitis, injection site reactions, skin nodules, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infections, blurred vision, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal impairment, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, anaphylactic reactions, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, phototoxic reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized vesicular fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, female infertility.

This medication should be stored in a tightly sealed container to prevent air or moisture ingress, with an appropriate storage temperature between 15 to 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness for a long time.

Appearance

A white capsule filled with white to pale yellow powder with a blue stripe on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle