Medication info

GC Wellbeing Amino Injection

Prescription medicationInjectionsApproval withdrawn
Ingredient · strength
L-Isoleucine›1.04g / 100mLL-Leucine›1.309g / 100mLL-Lysine Acetate›0.971g / 100mLL-Methionine›0.11g / 100mLAcetylcysteine›0.07g / 100mLL-Phenylalanine›0.088g / 100mLL-Threonine›0.44g / 100mLL-Tryptophan›0.07g / 100mLL-Valine›1.008g / 100mLL-Arginine›1.072g / 100mLL-Histidine›0.28g / 100mLGlycine›0.582g / 100mLL-Alanine›0.464g / 100mLL-Proline›0.573g / 100mLL-Serine›0.224g / 100mL
Manufacturer / importer
(주)녹십자웰빙
Appearance
A colorless, transparent solution filled in a colorless transparent glass vial for injection.
Packaging
100 mL per bottle, 250 mL per bottle, 500 mL per bottle
Approval status
Approval withdrawn

MFDS item code 201907902 · Notified 2019.11.13

This product's status changed to Approval withdrawn on 2024.11.06. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of severe liver dysfunction (including brain dysfunction) and hepatic coma
Who uses it
Adults
Adult dosage
Generally, for total amino acids, 1.5 g per day per kg of body weight (corresponding to 1300 mL per day for a weight of 70 kg) is administered as a maximum dose by intravenous drip. The rate of administration should not exceed 1.25 mL per kg of body weight over 60 minutes.

Ingredients

Manufacturer
(주)녹십자웰빙

Efficacy & effects

Treatment of severe liver dysfunction (including brain dysfunction) and hepatic coma

  • Brain dysfunction
  • severe liver dysfunction
  • hepatic coma
View approved original text

This medication can be used when there is severe liver dysfunction or liver failure, both with and without brain dysfunction or brain disease. It is also effective for the treatment of hepatic coma. In these situations, it supplies essential amino acids parenterally to support liver function and protect brain function. This helps improve the patient's condition and enhance treatment effects.

Dosage and Administration

Adult dosage

Generally, for total amino acids, 1.5 g per day per kg of body weight (corresponding to 1300 mL per day for a weight of 70 kg) is administered as a maximum dose by intravenous drip. The rate of administration should not exceed 1.25 mL per kg of body weight over 60 minutes.

Precautions

This medication must be used according to the physician's instructions. It should not be administered to patients with poor kidney function or high nitrogen levels in the blood, patients with liver dysfunction, patients with amino acid metabolism issues, patients with weakened heart function or heart failure, patients with pulmonary edema, patients with little or no urine output, patients in acidosis, patients receiving excessive fluid supply, patients with a history of myocardial infarction, patients with low sodium levels in the blood, patients in shock, and patients with hypoxia. It should be used cautiously in patients with edema due to sodium retention, kidney disease, pulmonary disease, a history of severe heart disease, and in diabetic patients, as allergic reactions or asthma attacks may occur due to sodium pyrosulfite contained in this medication. Rarely, hypersensitivity reactions such as skin rashes may occur; if symptoms appear, treatment should be discontinued. Gastrointestinal symptoms like nausea or vomiting, chest discomfort, palpitations, rapid heartbeat, and elevated blood pressure may occur. Caution is needed as acidosis may occur when administered in large amounts quickly. When administering this medication, it is essential to regularly monitor electrolyte balance and fluid status, and diabetic patients should frequently check their blood glucose levels. Additionally, it is important to regularly test serum proteins, liver function, and kidney function. There may be interactions with other medications, especially tetracycline antibiotics, which can reduce their effectiveness. It is safe not to mix this drug with other non-parenteral nutrition products. Pregnant or breastfeeding women should consult with a physician to carefully consider the risks and benefits before administering this medication. In children, the dosage may need to be reduced to prevent hyperammonemia due to immature liver function, and blood ammonia levels should be checked frequently. Elderly patients may have decreased body function, so care must be taken to adjust the administration speed and dosage. When administering, check for the presence of electrolytes, and ensure not to inject rapidly. The medication must be prepared according to body temperature, compounded and administered in a sterile state, and should not be used if color change or turbidity occurs in the solution. During storage, do not open the packaging, and do not use if leaking or deteriorated. Use it exactly according to the indicated dosage on the container.

Side effects and when to seek care immediately

Serious side effects

Hypersensitivity reactions such as rashes, respiratory distress, respiratory arrest, shock, bronchospasm, elevated BUN due to renal failure, shock, respiratory distress, bronchospasm

Mild side effects

  • Nausea
  • vomiting
  • rash
  • chest discomfort
  • palpitations
  • tachycardia
  • elevated blood pressure
  • acidosis
  • chills
  • fever
Show 13 more
  • headache
  • urinary tract spasm
  • metabolic acidosis
  • hypophosphatemia
  • alkalosis
  • hyperglycemia
  • diabetes
  • osmotic diuresis
  • dehydration
  • rebound hypoglycemia
  • elevated liver enzymes
  • vitamin deficiencies and excesses
  • electrolyte imbalances

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent exposure to air and is best kept at room temperature between 1 to 30 degrees Celsius. This helps maintain the drug's effectiveness and prevent deterioration.

Appearance and packaging

Appearance

A colorless, transparent solution filled in a colorless transparent glass vial for injection.

Package unit

100 mL per bottle, 250 mL per bottle, 500 mL per bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.