Medication info

Megabrolin Capsule (Asebrophylline)

Prescription medicationOralApproval withdrawn
Ingredient · strength
Acebrophylline›100mg / 1 capsule
Manufacturer / importer
LNC Bio Co., Ltd.
Appearance
Capsules with upper gray and lower white containing white to off-white powder
Packaging
30 capsules/bottle, 300 capsules/bottle
Approval status
Approval withdrawn

MFDS item code 201907802 · Approved 2019.11.07

This product's status changed to Approval withdrawn on 2024.04.22. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of respiratory diseases (bronchitis, asthma, sinusitis, etc.)
Who takes it
Adults
Adult dose
Adults: Administer acebrophylline 100 mg orally per dose twice daily.

Ingredients

Manufacturer
LNC Bio Co., Ltd.

Efficacy & effects

Treatment of respiratory diseases (bronchitis, asthma, sinusitis, etc.)

  • Airway obstruction disorders
  • mucus secretion disorders
  • acute respiratory diseases
  • chronic respiratory diseases
  • acute bronchitis
  • chronic bronchitis
  • bronchial asthma
  • sinusitis
  • rhinitis
View approved original text

This medication is used for respiratory diseases caused by airway obstruction and mucus secretion disorders such as acute and chronic bronchitis, bronchial asthma, sinusitis, and rhinitis.

How to take

Adult dose

Adults: Administer acebrophylline 100 mg orally per dose twice daily.

Precautions

This medication should not be used in specific patients. For example, patients allergic to this medication or any of its components or those with hypersensitivity to other xanthine drugs should not take it. Furthermore, individuals allergic to ambroxol, patients with acute myocardial infarction, hypotensive patients, those with severe liver or kidney function impairment, and breastfeeding women should also refrain from using this medication. Since this medication contains lactose, individuals with genetic issues such as galactose intolerance, lactase deficiency, or glucose-galactose malabsorption should not take it. Patients with heart disease, obesity, epilepsy history, peptic ulcer, hyperthyroidism, elderly individuals, children, hypertension, severe hypoxemia, chronic obstructive pulmonary disease, liver and kidney disorders, and pregnant or potentially pregnant women should use this medication cautiously. Additionally, individuals allergic or hypersensitive to the included yellow number 5 should take care as well. Various side effects such as nausea, dizziness, gastrointestinal discomfort, diarrhea, vomiting, rash, and respiratory distress may occur when taking this medication, so if symptoms arise, discontinue use immediately and consult a doctor. Increased blood concentration of this medication may lead to toxicity, so elderly patients, alcoholics, patients with heart disease, and those with impaired liver or kidney function should be especially cautious. When taken with other medications, interactions may occur, and if used alongside antibiotics, diuretics, anticoagulants, or central nervous system stimulants, it is necessary to inform a doctor or pharmacist, and dosage adjustments may be required. It is advisable for pregnant or breastfeeding women not to take this medication, especially during early and late stages of pregnancy. Elderly individuals and children require dosage adjustments and caution when using this medication. In case of overdose, severe convulsions or cardiac arrhythmias may occur, and immediate medical attention should be sought, and treatment should restart at a lower dosage afterward. Finally, this medication should be kept out of the reach of children and should not be transferred to other containers for safety.

Side effects

  • temporary area
  • dizziness
  • abdominal discomfort
  • gastric and abdominal distension
  • gastric and abdominal pain
  • diarrhea
  • constipation
  • nausea
  • vomiting
  • hematemesis
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  • heartburn
  • loss of appetite
  • gastric esophageal bleeding
  • epigastric pain
  • rash
  • urticaria
  • urticaria-like erythema
  • itching
  • facial swelling
  • dyspnea
  • elevated body temperature
  • purulent rhinitis
  • rapid breathing
  • oral paresthesia
  • arm paresthesia
  • headache
  • agitation
  • insomnia
  • tachycardia
  • extrasystole
  • hyperlaxity
  • hypotension
  • albuminuria
  • hyperglycemia
  • tonic-clonic seizure
  • ventricular arrhythmia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to maintain the storage temperature between 1 to 30 degrees Celsius at room temperature.

Appearance and packaging

Appearance

Capsules with upper gray and lower white containing white to off-white powder

Package unit

30 capsules/bottle, 300 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.