Yudron Injection (Evandron Sodium Dihydrate)

Adult administration

Administer 3 mg intravenously every 3 months for 15 - 30 seconds.

This medication must only be administered intravenously, and caution is necessary as administering it into an artery or around the injection site can cause tissue damage. Patients with allergies to this drug or its components, or with untreated hypocalcemia, should not use this medication. During use, gastrointestinal symptoms such as gastritis, diarrhea, abdominal pain, indigestion, nausea, and constipation, as well as musculoskeletal pain, joint pain, and muscle pain may occur. Additionally, flu-like symptoms such as fever, chills, fatigue, and muscle aches may temporarily appear at the start of administration. Rarely, severe allergic reactions such as skin rash, headache, vasculitis, and anaphylaxis may occur, so symptoms should be reported to medical personnel immediately. This medication may temporarily lower calcium levels, so patients must treat hypocalcemia or bone and mineral metabolism disorders before administration, and it is important to ingest sufficient calcium and vitamin D. Patients requiring dental treatment should undergo an oral examination before administration of this medication, and it is advisable to avoid excessive dental procedures during treatment. This medication may increase the risk of rare side effects such as osteonecrosis of the jaw and external auditory canal, as well as atypical fractures of the femur and other bones, so if there is pain in the legs or pelvis, medical personnel should be consulted immediately. It is recommended that pregnant or breastfeeding women do not use this medication. In case of overdose, careful monitoring of kidney and liver functions is required, and appropriate treatment is necessary if hypocalcemia occurs. This medication should not be mixed with calcium-containing solutions or other medications and must be administered intravenously. Keep out of reach of children, and do not reuse used syringes and needles; dispose of them safely.

Serious side effects

• Hives
• angioedema
• facial swelling/edema
• anaphylactic reaction/shock
• Stevens-Johnson syndrome
• erythema multiforme
• bullous dermatitis
• phlebitis/thrombophlebitis
• angioedema
• shortness of breath

Mild side effects

• Gastritis
• diarrhea
• abdominal pain
• indigestion
• nausea
• constipation
• musculoskeletal pain
• joint pain
• muscle pain
• flu-like symptoms

This medication should be stored in a sealed container to prevent exposure to air or moisture. It is best to maintain a storage temperature between 1 degrees and 30 degrees Celsius at room temperature. Proper storage will help maintain the effectiveness of the medication.

Appearance

It is an injection in a colorless and transparent solution contained in a colorless and transparent glass prefilled syringe, with a single-use syringe needle attached.

Package unit

3ml x 1 vial