Entisimba Tablet 20 mg (Simvastatin)

Adult dose

For adult patients, a dose of 40 mg per day is given to reduce the risk of cardiovascular disease. The typical starting dose for hyperlipidemia treatment is 20 mg given once in the evening, while patients with mild to moderate hypercholesterolemia may start at 10 mg. The dosage can be adjusted according to treatment response with administration of 5 to 40 mg once daily in the evening. For specific patient groups, dosage limits are as follows

Child dose

The recommended initial dose for pediatric patients (ages 10-17) with heterozygous familial hypercholesterolemia is 10 mg once daily in the evening with a recommended dosage range of 10 to 40 mg per day and a maximum dose of 40 mg per day.

This medication is primarily used to lower blood cholesterol levels. When taking this medication, symptoms such as muscle pain or weakness may occur, so any such symptoms should be promptly reported to a physician. Especially when taking high doses or certain other medications together, the risk of muscle problems may increase. Patients with liver dysfunction or a history of liver disease should not take this medication and should have regular liver function tests. Women who are pregnant, may become pregnant, or are breastfeeding should not take this medication, and if pregnancy occurs during treatment, it should be stopped immediately. This medication may increase blood concentrations and the risk of side effects when taken with certain enzyme-inhibiting medications, so it is important to inform the physician or pharmacist of any other medications being taken. Elderly patients, patients with reduced kidney function, or patients with hypothyroidism should use this medication with caution, and regular testing is required. It is advisable to avoid certain foods, such as grapefruit juice, during the course of this medication. When receiving a new prescription from another physician while taking this medication, it is essential to inform them about this medication. In case of an overdose, general treatment is required, and the medication should be stored out of reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucous membranes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme fatigue, sudden and very severe headaches, lightning pains, seizures, confusion, visual disturbances, paralysis, urination problems

Mild side effects

Abdominal pain, fatigue, constipation, diarrhea, indigestion, bloating, nausea, headache, upper respiratory infection, atrial fibrillation, gastritis, diabetes, muscle pain, insomnia, dizziness, bronchitis, eczema, urinary tract infection, alopecia, itching, various skin changes, drug rash resembling lichen planus, gynecomastia, decreased libido, sexual dysfunction, cataract progression, ocular muscle paralysis, anemia, temporary and mild elevations in liver function tests, thyroid function abnormalities, fasting blood sugar

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is best to maintain storage temperatures between 1 and 30 degrees Celsius to preserve the drug's effectiveness over time.

Appearance

Pale yellowish oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle