Cofromin Capsule 300 mg (Theobromine)

Adult dose

Adults: Administer 1 capsule per dose orally twice daily

This drug should not be used in patients who have hypersensitivity to xanthine drugs or have experienced severe side effects from xanthine drugs in the past. Caution should be exercised in patients with peptic ulcers, convulsive symptoms, severe acute infectious lung diseases or tuberculosis, liver or kidney dysfunction, congestive heart failure, alcohol addiction, hypoxia, hypertension, hypertrophic cardiomyopathy, tachyarrhythmias, myocardial infarction, and hypotension. Typical side effects may include headache, dizziness, nausea, and sometimes itching, rash, drowsiness, myalgia, insomnia, abdominal distension, loss of appetite, constipation, diarrhea, dry mouth, dysphagia, heartburn, vomiting, abdominal pain, stomach pain, indigestion, and other symptoms. Additionally, there may be an increase in uric acid levels in the blood or liver function tests may rise, along with symptoms such as edema, facial swelling, palpitations, sore throat, fever, and sweating. Careful monitoring is needed because this drug may be slowly excreted in patients with viral infections, impaired liver and kidney functions, elderly patients, and those with heart failure. There may be interactions with other xanthine drugs such as caffeine-containing beverages, aminophylline, theophylline, so caution is warranted. Also, caution is needed when used conjointly with central nervous system stimulants or sympathomimetics like cocaine, amphetamines, and codeine. When used with several other medications, this drug may influence its excretion rate or blood concentration, so consultation with a pharmacist or physician is recommended. Women who are pregnant or breastfeeding must consult their physician before taking this drug, and caution is necessary if there is a possibility of pregnancy. This drug should not be used in children or adolescents under 18 years of age or in elderly patients over 70 years, as safety and efficacy have not been sufficiently established for these populations. In case of overdose, serious symptoms such as nausea, vomiting, headache, anxiety, seizures, and cardiac arrhythmias may occur, requiring immediate medical attention.

• Headache
• dizziness
• nausea
• itching
• rash
• drowsiness
• muscle pain
• insomnia
• abdominal fullness
• loss of appetite

This medicine should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain storage temperatures between 1 to 30 degrees Celsius to ensure the drug's effectiveness and safety.

Appearance

Hard capsule filled with white powder, with a dark yellow upper part and a white lower part

Package unit

30 capsules/bottle, 300 capsules/bottle