Nelson Donepezil Tablets 10 mg (Donepezil Hydrochloride Hemihydrate)

Adult dose

Administer Donepezil Hydrochloride at a dose of 5 mg once daily before bedtime. After administering 5 mg for 4 to 6 weeks and assessing clinical response, the dose may be increased to 10 mg. When increasing to a dose of 10 mg per day, monitor for gastrointestinal adverse reactions carefully. Women aged 85 and older who are underweight should not exceed 5 mg per day and must be monitored closely.

This medication contains Donepezil Hydrochloride as the main ingredient and is primarily used for the treatment of symptoms of Alzheimer's disease. This medication should not be used in certain patients. For example, individuals allergic to this drug or its components, pregnant women or those who may become pregnant, and breastfeeding women should not take it. Additionally, patients with genetic lactose intolerance or specific lactase enzyme deficiencies should not take this medication as it contains lactose. Patients with heart conditions, especially those with bradycardia or cardiac conduction disorders, should use this medication cautiously, as it may lower heart rate or cause arrhythmias. Patients currently taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers may experience worsened symptoms due to increased gastric acid secretion and enhanced gastrointestinal motility, so caution is required. Patients with a history of asthma or obstructive pulmonary disease should be careful when taking this drug, as it may worsen their condition by causing bronchial constriction and increased mucus secretion. Furthermore, patients with extrapyramidal disorders such as Parkinson's disease may experience exacerbation of symptoms due to the cholinergic action of this drug. This medication contains specific pigments (Coloring 5), and those allergic to or sensitive to this component should be administered with caution. A variety of side effects may occur with the use of this medication, including nausea, vomiting, diarrhea, dizziness, insomnia, fatigue, muscle pain, heart-related abnormalities (bradycardia, heart block, etc.), liver function impairment, and rashes have been reported. Serious adverse reactions may include fainting, myocardial infarction, hepatitis, cerebral hemorrhage, seizures, and severe muscle abnormalities. If these symptoms occur, stop taking the medication immediately and seek medical attention. This medication is not approved for other forms of dementia or memory disorders other than Alzheimer's disease and should be administered under the supervision of an experienced physician. Patients with cardiovascular conditions require particular attention, and regular monitoring such as ECG is recommended. This medication may affect the ability to drive or operate machinery, so caution is necessary during the initial dosing or when changing the dose. Additionally, this medication may interact with various drugs, so patients taking other medications should consult their physician or pharmacist. Pregnant or breastfeeding women should ideally avoid this medication, and if necessary, consult a specialist. Safety in children has not been established, and it should not be used in pediatric patients. In the case of overdose, severe symptoms such as nausea, vomiting, bradycardia, and respiratory depression may appear, and immediate medical treatment is necessary. This medication should be kept out of the reach of children, and it is advised not to transfer it to another container.

Serious side effects

Fainting, bradycardia, heart block, prolonged QT interval, myocardial infarction, heart failure, peptic ulcers, perforated duodenal ulcer, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, cerebral seizures (epilepsy, convulsions), cerebral hemorrhage, cerebrovascular disorders, extrapyramidal disorders (movement dysfunction, ataxia, movement disorders, dystonia, tremors, involuntary movements, gait disturbances, abnormal posture, speech disorders), neuroleptic malignant syndrome (akinetic mutism, extreme rigidity,

Mild side effects

Nausea, vomiting, diarrhea, reduced appetite, dizziness, insomnia, drowsiness, headache, fatigue, muscle pain, rashes, itching, incontinence, urinary disturbances, anxiety, hallucinations, tremors, gait disturbances, involuntary movements, reduced concentration, mental dullness, sweating, blood pressure fluctuations, muscle cramps, abdominal pain, reduced body temperature, thrombocytopenia, anemia, swelling without increased blood pressure, flushing, weight loss, lethargy, malaise, dehydration, hyperlipidemia,

This medication should be stored in a tightly closed container to prevent air or moisture from entering. The storage temperature should be maintained between 1 and 30 degrees Celsius (Room temperature) for optimal effectiveness.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle