Ivandox Injection (Ibandronate Sodium Monohydrate)

Adult administration

3mg is administered as an intravenous injection every 3 months over 15-30 seconds. Patients are advised to additionally take calcium and vitamin D supplements. If a scheduled dose is missed, administer the injection as soon as possible and continue regular dosing every 3 months thereafter.

This medication must be administered via intravenous injection, and great caution should be taken as injecting into arteries or around veins may cause tissue damage. Do not use in patients who are allergic to this medication or its components, or in patients with untreated hypocalcemia. This medication may temporarily lower serum calcium levels; therefore, hypocalcemia or metabolic bone and mineral disorders should be treated before use, and adequate intake of calcium and vitamin D is important. During the treatment period, regular medical check-ups are required, particularly for patients with renal dysfunction or those taking medications that may affect the kidneys. Osteonecrosis of the jaw may occur during treatment with this medication, so patients with risk factors should have a dental examination prior to treatment and avoid excessive dental work during treatment. Additionally, this medication may cause various side effects such as myalgia, arthralgia, dyspepsia, headache, rash, etc., so if any abnormal symptoms occur, immediate consultation with a healthcare professional is necessary. Pregnant or breastfeeding women should avoid using this medication as its safety has not been established. In case of overdose, serum calcium, phosphorus, and magnesium levels may decrease abnormally, so appropriate treatment and monitoring are necessary. This medication should not be mixed with other calcium-containing solutions or intravenous medications, and syringes and needles should not be reused and should be disposed of safely.

Serious side effects

Hives, angioedema, facial swelling/edema, anaphylactic reaction/shock, exacerbation of asthma, Stevens-Johnson syndrome, erythema multiforme, bullous dermatitis, osteonecrosis of the jaw and external auditory canal, uveitis, episcleritis, scleritis, multiple organ failure, death, thrombophlebitis/phlebothrombosis, vascular abnormalities, dyspnea.

Mild side effects

Gastritis, diarrhea, abdominal pain, dyspepsia, nausea, constipation, musculoskeletal pain, arthralgia, myalgia, influenza-like illness (including arthralgia, myalgia, fever, chills, fatigue, nausea, loss of appetite, bone pain), fatigue, headache, rash, lower back pain, weakness, injection site reactions, sensory loss, dizziness, fever, hypothyroidism, peripheral neuropathy, hearing loss, skin peeling, insomnia, anxiety, tinnitus, lipomas, ocular hemorrhage, heart failure.

Store this medication in a sealed container to protect it from air exposure, and maintain the storage temperature between 1 to 30 degrees Celsius to ensure safe preservation of its effectiveness.

Appearance

A colorless and transparent solution packaged in a colorless and transparent glass prefilled syringe with a single-use injection needle attached.

Package unit

3ml x 1 vial