Altitok Soft Capsule 30mg (Alitretinoin)

Adult dose

Take 10~30mg once daily with a meal or immediately after a meal. It is preferable to take it at the same time each day. The initial dose is 30mg of alitretinoin; reduce the dose to 10mg according to adverse reactions. Patients with diabetes, obesity, cardiovascular risk factors, or dyslipidemia: The initial dose is 10mg and may be increased to 30mg if necessary, depending on tolerability and efficacy. Periodic monitoring of the blood lipid profile and blood glucose may be needed during treatment with this medicine. Discontinue treatment as soon as the treatment goal of clear or almost clear hands is achieved. Discontinue treatment if hand eczema remains severe after the initial 12 weeks of treatment, and also discontinue if the treatment goal has not been achieved by 24 weeks of treatment.

This medication must not be used by women who are pregnant or may become pregnant. It may cause serious birth defects, so pregnancy tests must be conducted before and during treatment. Effective contraception must be diligently practiced, and at least two effective contraceptive methods should be used concurrently. Regular monitoring of blood triglyceride and cholesterol levels is necessary during treatment, and any abnormalities must be reported immediately. Special caution is required for patients with hypertriglyceridemia due to the risk of acute pancreatitis. Psychiatric symptoms, such as depression or mood changes, may occur, so mental health status should be monitored periodically. Should symptoms such as depression or suicidal thoughts arise, medical personnel must be notified immediately. Dry eyes or changes in vision may occur, and if these symptoms are severe, treatment should be discontinued and a physician consulted. This medication is not used in patients with poor liver or kidney function, uncontrolled hypothyroidism, or vitamin A excess. Interactions with other medications may occur, so it is essential to inform the doctor or pharmacist of any other medications being taken. Overdose can lead to severe headache, diarrhea, facial flushing, and other symptoms; in such cases, immediate medical attention is required. When taking this medication, it should be swallowed with water during or right after meals, and not chewed. This medication must be stored out of the reach of children, away from direct sunlight, and in a cool place below 30 degrees Celsius. The physician, pharmacist, and patient must all fully understand and comply with the relevant guidelines under the pregnancy prevention program, and this medication must not be shared with others.

• Headache
• erythema
• flushing
• increased triglycerides
• elevated cholesterol
• decreased thyroid-stimulating hormone
• decreased free T4
• anemia
• increased iron-binding capacity
• decreased monocytes

This medication should be stored in a tightly sealed container that blocks light, at temperatures between 1 degree and 30 degrees Celsius at room temperature. Storing it this way will prevent changes to the medication’s ingredients and ensure effectiveness is maintained.

Appearance

Brown oval soft capsule containing a uniform yellow to yellow-green liquid

Package unit

30 capsules/box [(10 capsules/PTP x 3)]