Aliderm Soft Capsule 10mg (Alitretinoin)

Adult dose

Take 10~30mg once daily with a meal or immediately after a meal. It is preferable to take it at the same time each day. The initial dose is 30mg of alitretinoin; reduce the dose to 10mg according to adverse reactions. Patients with diabetes, obesity, cardiovascular risk factors, or dyslipidemia: The initial dose is 10mg and may be increased to 30mg if necessary, depending on tolerability and efficacy. Periodic monitoring of the blood lipid profile and blood glucose may be needed during treatment with this medicine. Discontinue treatment as soon as the treatment goal of clear or almost clear hands is achieved. Discontinue treatment if hand eczema remains severe after the initial 12 weeks of treatment, and also discontinue if the treatment goal has not been achieved by 24 weeks of treatment.

This medication must not be used in women who are pregnant or may become pregnant. There is a very high risk of causing serious birth defects in the fetus. A pregnancy test must be performed prior to taking this medication, and regular pregnancy tests should be conducted during treatment and after treatment has ended. During treatment, it is necessary to use two or more effective contraceptive methods, and if contraceptive failure occurs, consult a physician immediately. If triglyceride levels in the blood are very high, serious side effects such as acute pancreatitis may occur, so blood cholesterol and triglyceride levels should be monitored regularly. If any abnormal symptoms appear, discontinue use immediately and seek medical attention. Patients with a history of mental illness or symptoms of depression need to exercise caution when taking this medication. If changes in mood or depressive symptoms occur during treatment, consult a physician immediately. This medication can cause dryness of the skin and lips, so it is advisable to use moisturizers to protect the skin. Sensitivity to ultraviolet light is increased, so excessive sun exposure or phototherapy should be avoided, and it is recommended to use sunscreen when going outdoors. Wearing contact lenses may be difficult, so it is advisable to use glasses during the period of taking this medication. If symptoms such as headaches, dizziness, or visual disturbances occur, inform your physician immediately. Especially, if there are headaches accompanied by nausea, vomiting, or visual impairment, discontinue use immediately. This medication increases the risk of side effects when combined with other vitamin A preparations or tetracycline antibiotics, so they should not be taken together. Take this medication with food or immediately after a meal, and it is advisable to swallow it whole with sufficient water without chewing the tablet. This medication should be kept out of reach of children, stored in a cool place below 30 degrees Celsius, and shielded from direct sunlight. During treatment, avoid vigorous exercise, do not share this medication with others, and after discontinuation, refrain from donating blood for a certain period.

• Headache
• erythema
• flushing
• increased triglycerides
• increased cholesterol
• decreased thyroid-stimulating hormone
• decreased free T4
• anemia
• increased iron-binding capacity
• decreased monocytes

This medication may be sensitive to light, so it should be stored in a tightly sealed container that protects it from light. Additionally, it is important to store it at a temperature between 1 and 30 degrees Celsius to maintain its efficacy.

Appearance

A brown oval soft capsule containing a uniform yellow to yellowish-green liquid.

Package unit

30 capsules/box [10 capsules/PTPX3]